Posted by admin on Apr 23, 2016 in |
To access the quality of drug the standardization is very critical. As per WHO guidelines, 80% of the peoples have relied on traditional medicine in a rising nation. Most of the conventional system is valuable but a lack of standardization. The parameters studied are physicochemical parameters, phytochemical parameters & qualitative chemical tests. These values will help to obtain the batch to batch variation in traditional preparation of Mehari Choorna which is used to treat diabetes mellitus. We calculated and discussed extractive values, moisture content and ash value. The scientific method for its quality and safety evaluation is not yet to be documented. Hence in the current work, an attempt has been made to evaluate the quality parameters to be used for its preparation and...
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Posted by admin on Apr 23, 2016 in |
Over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the endangerment of certain medicinal plant species. Shortly, many plant species may be unavailable for the use of industry due to over-exploitation. The present study outlines the concept of plant part substitution. The studies were carried out in Ailanthus excelsa to evaluate the possibilities of using small branches in place of stem bark which will help sustainable utilization. Stem bark and small branches of Ailanthus excelsa are compared by the physicochemical analysis, phytochemical analysis, total phenolic contents, total flavonoid contents and High-Performance Thin Layer Chromatography (HPTLC). Phytochemical analysis and HPTLC of n-hexane, ethyl acetate, and ethanol extracts showed many similarities which suggest that small branches may have nearly similar active potency like stem bark and may provide the base for further study to use small branches as a substitute of stem bark of Ailanthus excelsa. The study will be helpful in identification and quality control of Ailanthus excelsa and can...
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Posted by admin on Apr 23, 2016 in |
Protective effect of the probiotic combination of usnic acid and Lactobacillus casei in experimentally induced ulcer in rats was investigated. Rats inward usnic acid (100 mg/kg), L. casei (10-8 con.), usnic acid (100 mg/kg) + L. casei (10-8 con.), and omeprazole (30 mg/kg) twice daily for 5 days for prevention against aspirin (ASP), ethanol (EtOH), cold restraint stress (CRS) and pylorus ligation-induced ulcer (PL). The results of the present study showed the first time that the usnic acid (100 mg/kg) + L. casei (10-8 con.) as probiotic combination significantly inhibited the ulcer index in ASP, EtOH, CRS and PL to 3.4 ± 0.12, 6.3 ± 1.8, 3.4 ± 0.8 and 4.3 ± 0.9 (p<0.001) respectively, as compared to control group (19.2 ± 1.6, 22.5 ± 6.3, 24.2 ± 3.2, 14.2 ± 2.7). Besides usnic acid (100 mg/kg) + L. casei (10-8 con.) offered protection (72%, p<0.001) against ethanol-induced depletion of gastric wall mucus. The usnic acid (100 mg/kg) + L. casei (10-8 con.) showed significant inhibition of lipid peroxidation...
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Posted by admin on Apr 23, 2016 in |
Cardaria draba commonly known as whitetop or hoary cress is a perennial herb that is native to Eastern Europe and eastern Asia, including Iran. In this study, the effects of alcoholic extract of Cardaria draba (25, 50 and 100 mg/kg) via oral gavage for 2 weeks alone and on scopolamine (1 mg /kg/d, 4 days, i.p.) – zinc chloride (75 mg/kg/d, 2 weeks oral gavage) – and sodium metavanadate (22.5 mg/kg/d, 2 weeks oral gavage) – induced avoidance memory retention alterations were investigated in the step-through passive avoidance task. Zinc chloride and scopolamine were dissolved in saline and sodium metavanadate were dissolved in animal’s drinking water. At the end of each part of studies, animals were trained for one day in a step-through task. The avoidance memory retention alterations were evaluated 24 h, 48 h, 96 h and 168 h later to the training session. Zinc chloride and sodium metavanadate oral gavage for 2 weeks decreased latencies compared to control animals. Also, four days intra-peritoneal injection of scopolamine decreased...
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Posted by admin on Mar 13, 2016 in |
Trianthema decandra Linn., belongs to family Aizoaceae, commonly known as “Punarnavi” in Sanskrit, “Gadabandi” in Hindi, and “Vellai sharuni” in Tamil. This plant is globally distributed tropical and subtropical regions. In India, it grows in dry-soil lands. It has been known since ancient times for curative properties and has been utilized for treatment of various ailments such as burns and wounds. The roots are aperients and said to be useful in hepatitis, asthma, and suppression of the menses. A decoction of the root-bark is given as an aperients. The juice of the leaves dropped into the nostrils relieves one-sided headache. 1 In the present investigation, the detailed Pharmacognostic study of Trianthema decandra root is carried out to lay down the standards, which could be useful in future Forensic identification of unknown plant material. Results: The study includes macroscopic, microscopic, preliminary phytochemical screening and physicochemical evaluation. The objective this was to characterize the unknown plant material. Conclusion: In recent years there has been a rapid increase in the standardization of...
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