Posted by admin on Jul 11, 2017 in |
Lantana indica Roxb. (Verbenaceae) is grown as an ornamental plant in tropical and subtropical regions of the world. The plant is used to treat asthma, abdominal disorders, bilious fever, cancer, catarrhal infections, chicken pox, eczema, hypertension, malaria, measles, swelling, rheumatism, tetanus, and ulcers. Phytochemical investigation of a methanolic extract of the leaves led to isolating three new chemical constituents characterized n-heneitriacont-4-en-16β, 17β, 18β-triol (n-heneitriacontenol, 3), 6, 4′- dimethoxy- 7, 3′- dihydroxy flavone- 7- O- β-D-glucopyranoside (lantanaflavone 7-O-β-D-glucoside, 6), urs-12-en-3β-ol-28-oic acid 3β-D-glucopyranosyl-6´-octadecanoate (ursolic acid 3-O-β-D-glucosyl-6′-oleate, 8) along with five known compounds characterized as n- hexadecanyl oleate (1), n-octadecanyl oleate (2), oleanolic acid (4), ursolic acid (5) and oleanolic acid 3-O-β-D-glucopyranoside (7). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical...
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Posted by admin on Jul 11, 2017 in |
Teucrium polium L. is a member of the Lamiaceae family and is represented in the Flora of Syria by two variety: Teucrium polium var. angusti folium and Teucrium polium var. mollissimum. Teucrium polium is a wild-growing flowering plant, found abundantly in Syria, and it is used traditional medicine for it’s diuretic, antipyretic, antispasmodic, tonic, anti-inflammatory, antihypertensive, anorexic, analgesic, antibacterial and antidiabetic effects. Several reports have demonstrated a wide range of beneficial biological and pharmacological activities of the phenylethanoid, phenylpropanoid, and flavonoid components, while the furano neo-clerodane diterpenoids present in germander have been implicated in the in-vivo hepatotoxicity of this botanical. Phytochemical studies of this plant have been carried out. Aerial parts of the plant were extracted with petroleum ether at room temperature, and then extract with methanol in Soxhlet, and finally extract with aqueous methanol at room temperature successively. Fractionation of the methanol extract by column chromatography and purification by crystallization yielded three known flavonoids Cirsimartin 2, Cirsiliol 3, and Apigenin 4. The aqueous methanolic extract yielded one new...
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Posted by admin on May 30, 2017 in |
Anxiety is an obnoxious condition of inner disorder, often accompanied by thoughts, somatic complaints, and nervous behavior. Anxiety is initiated by external stimuli. It may be as a consequence of any underline disease condition such as Parkinson’s disease, rheumatoid arthritis, or diabetes. There are different types of anxiety which are a social anxiety disorder, selective mutism, agoraphobia, specific phobia, panic attack, and separation anxiety disorder. In this study anxiolytic activity of methanolic and ethanolic extract of Leaves of Trachyspermum ammi has been determined. For this purpose methanolic and ethanolic extract of Trachyspermum ammi leaves were prepared and evaluate anxiolytic activity in-vivo on mice by using light and dark model of anxiety. Data analysis by using two way ANOVA gives highly significant results, i.e. (P<0.000) for both methanolic and ethanolic extract of Trachyspermum ammi...
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Posted by admin on May 30, 2017 in |
The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus using streptozotocin in normal Albino wistar rats and study the anti-diabetic activity of polyherbal formulation by comparison of changes in levels of glucose between normal and diabetic rats. The effect of methanol extract of polyherbal preparation containing aerial parts of Schrebera swietenoides, roots of Barleria montana and aerial parts of Rotula aquatica was investigated in normal and streptozotocin-induced diabetic rats. The lowest blood glucose levels were observed at 4 and 8th h after the oral administration of 150 and 300 mg/kg b.w polyherbal formulation. The blood glucose levels at 24 h after the oral administration of 150 and 300 mg/kg b.w. of the polyherbal formulation was significantly lowered the blood glucose...
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Posted by admin on May 30, 2017 in |
Mangiferin content in aqueous extracts of 30 varieties of Mangifera indica leaves collected from Gujarat state of Western India has been estimated during this study, using a simple reverse phase HPLC-DAD analysis method. The proposed method has been validated according to ICH guidelines in terms of linearity, accuracy, intraday and interday precision, limit of detection and limit of quantitation. The calibration graph was found to be linear over a concentration range of 20-120 µg/mL, with a regression coefficient of 0.9943. Determination of accuracy by standard addition method at three different concentration levels returned a mean recovery value of 97.64%. Average intraday and interday precision values were found to be less than...
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