Posted by admin on Jul 31, 2018 in |
Purpose: The aim of the present study was to investigate the wound healing activity of the selected Indian medicinal plants Terminalia chebula, Terminalia bellarica, Ficus racemosa, Piper nigrum, Zingiber officinalis. Method: Excision and incision models for diabetes-induced rats at specified varying doses. Result: The plants showed a definite, positive effect on wound healing. Conclusion: The efficacy of these plants in wound healing may be due to its action on antioxidant enzymes, thereby justifying the traditional...
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Posted by admin on Jul 31, 2018 in |
ABSTRACT: Context: Syzygium cumini (L.) Skeels (Myrtaceae) is popularly known to have various pharmacological and traditional uses. Before this study, there were no claims reporting its potential use for dengue by increasing platelet and leukocyte levels. Objectives: The effects of the methanolic extract of S. cumini leaves on the platelet and leukocyte levels were evaluated in Sprague-Dawley rats at doses 400 mg/kg and 800 mg/kg body weight. Methodology: The bioassay utilized 24 rats that were divided into four groups (n = 6) where hydroxyurea was used to induce depletion of platelet and leukocyte levels in all groups. After induction, oral treatment of methanolic extract was given daily to the treatment groups for six days. The platelet and leukocyte counts were measured before induction to get the baseline, after induction, and at the 1st, 3rd, and 6th day of treatment. High-performance liquid chromatography (HPLC) analysis was also conducted to identify the phenolic compounds present in the extract. Results: Results revealed that the methanolic extract of S. cumini caused an increase...
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Posted by admin on Jul 31, 2018 in |
As a source of remedies, medicinal plants are widely used as alternative medicines for the treatment or prevention of many diseases. Ficus hispida is traditionally used for treating diarrhoea, wounds, pain, inflammation, diabetes, fever, and neurological disorders. To evaluate the qualitative phytochemical constituents and antidiarrhoeal activity of methanolic extract of Ficus hispida leaves the present study was designed. Phytochemical constituents and anti-diarrhoeal activities were determined and assessed by various tests such as Molisch’s test, Fehling test, Mayer’s test, frothing test, FeCl3 test, alkali test, Salkowski’s test, Keller-killiani test and CuSO4 test, castor oil, and MgSO4 induced diarrheal test. This extract figured the presence of carbohydrates, flavonoids, tannins, glycosides, triterpenoids, fat and fixed oils. Moreover, both doses of (200 mg/kg and 400 mg/kg) methanolic extract of Ficus hispida leaves significantly (p<0.05, vs. control) reduced the gastrointestinal motility and inhibited the percentage of diarrhoea in antidiarrhoeal models. But 400 mg/kg dose showed better antidiarrhoeal activity than 200 mg/kg dose compared to control in both antidiarrhoeal tests. The results indicate that Ficus...
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Posted by admin on Jul 31, 2018 in |
The emergence of anti-malarial resistant parasites has posed a serious threat to the control and elimination of malaria. Therefore, there is a need for an alternative drug that is highly efficacious, affordable and safer for the treatment of malaria; hence, interest is now on the use of herbal medicine to treat malaria. Ogidi community in the Anambra State of Nigeria depends mainly on plants for the treatment of malaria. Bixa orellana plant, belonging to the family Bixaceae, is a very popular medicinal plant in Nigeria where it is used to treat malaria, jaundice, diarrhoea, dysentery, hypertension, as well as diabetes. The ethnomedicinal use against malaria prompted this investigation on the anti-plasmodial activity of the leaf of Bixa orellana. Bixa orellana leaves were obtained from Ogidi, Anambra, Nigeria, it was dried and pulverized to smaller particle size and extraction was by cold maceration with methanol which was fractionated into n-hexane and ethyl acetate fractions. The phytochemical analysis was carried out using standard procedures. The evaluation of anti-malarial activity was done...
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Posted by admin on Jul 31, 2018 in |
Hypertension is a common clinical problem encountered in day-to-day practice. Although several synthetic pharmaceutical drugs already exist for the treatment of hypertension, these drugs can develop many complicated side effects. On the other hand in our Arabian countries, patient compliance forces the population to frequently recourse to traditional medicine which mainly uses plants. Because of most of the medicinal agents including herbs were reported to have potentially unexpected effects including toxicity and interactions, this study focused on the investigation of antihypertensive activity of four plants mixture along with studying their interaction. In this study ethanolic extract of a mixture composed of four plants Hyphaene thebaica, Olea europaea, Origanum majorana, and Hibiscus sabdariffa was investigated for its antihypertensive activity and interaction between it’s including herbs. 50 g of each plant powder was mixed homogeneously and macerated in 70% ethanol for about 7 days. The effect of this extract was investigated at a dose level of 25 mg/kg. Blood pressure was measured by a non-invasive blood pressure recorder apparatus before and...
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