Posted by admin on Jun 2, 2018 in |
This paper presented the traditional uses of 20 plant species belonging to 14 families that are used by the Santal tribal practitioners in Tanore Upazila of Rajshahi district, Bangladesh for the treatment of diarrhoea and dysentery diseases. During the study, interviews were conducted with the help of a semi-structured questionnaire and the guided field walks method. The medicinal plants traditionally used by Santal tribes were collected and preserved as herbarium specimens by following the standard methods. The identification of plants was further authenticated with the Herbarium, Department of Botany, Rajshahi University, Bangladesh. For each species, scientific name, local name, family name, parts used and mode of uses were provided. All these plants need to be evaluated through phyto and pharmacochemical investigations to discover their potentiality and may help in developing effective drugs for human health...
Read More
Posted by admin on Jun 2, 2018 in |
Objective: To study the preliminary and pharmacognostic characteristics of Ziziphus mauritiana Lam., harvested in Côte d’Ivoire. Identify the drug by anatomy and histochemistry. Method: Macroscopic and microscopic study of the fresh and dry drug and determination of physicochemical parameters. Results: Tree, shrub or bush, 16 m long, 5 m or 4 m, Ziziphus mauritiana Lam. Has bending branches with rounded tops. Its fairly cracked bark is gray or brown, then pale red. The oval or sub-orbicular leaves are alternate and petiolate from 4 mm to 5 mm. The limb, dark green in color, is polished on the upper side and whitish and then densely tomentose on the lower side. The anatomo-histological cut of the limb showed a median rib slightly curved on the upper surface and strongly bulging on the lower side and a broader limb. Each epidermis consisted of small, visible cells more or less rectangular, is covered with a cuticle, outer lipoidal covering; impermissive and resistant, giving it a protective role. The cross-section of the stem, revealed...
Read More
Posted by admin on Jun 2, 2018 in |
The inhibitory effect of Juniperus phoenicea leaves extracts on Xanthine Oxidase activity was evaluated spectrophotometrically at 290 nm. Extracts of Juniperus phoenicea showed a potent XO inhibitory activity. To isolate the active compounds, an in-vitro bio-guided fractionation was undertaken by preparative chromatographic techniques. Fractions 2, 3 and 6 of ethyl acetate extract demonstrated substantial XO inhibitory activity (>80% inhibition) at 400 μg/mL. The highest inhibitory effect was obtained for fraction 3 (87.8%). The major constituents amentoflavone (1) and catechin (2) isolated from the fraction 3 were identified by extensive spectroscopic studies including 1D and 2D NMR experiments. These two compounds have no inhibitory effect on xanthine oxidase; it is deduced that the XOI activity of the fraction 3, was due either to a minor bioactive compound or possible synergisms. However, this study showed that the tested plant species are a potential source of natural XO inhibitors that can be developed, upon further investigation, for treatment of gout and other XO-related...
Read More
Posted by admin on May 2, 2018 in |
The present research aimed at scrutinizing the role of Mahua Oil (MO) as a suppository base which can enhance the release of drug in the site of administration. Three formulations were designed with erythromycin as the drug utilizing; F1 (MO and Beeswax in the ratio of 3:1), F2 (MO and PEG 6000 in the ratio of 1:1), and F3 (cocoa butter – 100%) as the base material. The suppositories were prepared using pour molding method after suitable calibration of molds. All the formulations were characterized in terms of breaking strength, disintegration time, drug content, in-vitro dissolution, and accelerated stability studies. The MO containing formulations displayed a good breaking strength, optimized disintegration time, and higher drug content as compared to the cocoa butter formulation. The optimized formulation F2 represented the optimized release of 81.35% over the range of 1 h. A little difference in drug content (1.78%), breaking strength (0.2 Kg/cm2), and disintegrating time (0.6 min) was observed in the accelerated stability study. The study concluded that MO has a...
Read More
Posted by admin on May 2, 2018 in |
Anatomical characters and thin layer chromatographic fingerprint of root, root-bark and leaf of Agnimanthaḥ (Premna serratifolia L.), an important drug used in Ayurvedic system of medicine has been studied in detail to identify the original drug from the...
Read More