Posted by admin on Feb 28, 2026 in |
Infertility is a growing global health concern affecting both men and women. In tribal regions of India, traditional medicinal plants remain the primary source of treatment for reproductive disorders. The Akola region of Ahilyanagar District (Maharashtra) possesses a profound, traditional knowledge base on botanicals that boost reproductive health. Objective: The present study aims to document fertility-promoting medicinal plants used by tribal communities of the Akola region and to correlate traditional claims with available pharmacognostic, phytochemical, and pharmacological evidence. Materials and Methods: Ethnobotanical surveys were conducted through personal interviews with tribal healers and elderly practitioners. Plants were identified botanically and validated using standard floras. Literature analysis was performed using Scopus, PubMed, and peer-reviewed pharmacognosy journals to evaluate pharmacological mechanisms. Results: A total of 40 medicinal plant species belonging to 29 families were documented. These plants are traditionally used as fertility enhancers, aphrodisiacs, or reproductive tonics. Pharmacological evidence indicates mechanisms such as antioxidant activity, hormone modulation, adaptogenic action, and gonadoprotective effects. Conclusion: Traditional fertility-promoting plants of the Akola region possess significant...
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Posted by admin on Feb 28, 2026 in |
Vitex madiensis, consumed daily as a tea named Tikoni, is widely used in traditional medicine in Congo Brazzaville to treat fever, pain, inflammation, malaria, dysentery, female infertility, mental illness and epilepsy. Its aqueous leaf extract does not exhibit acute toxicity. Its pharmacological effects against pain, inflammation, insomnia, oxidative stress, and Plasmodium falciparum are very promising. The objective of this study was to investigate the subchronic toxicity of its aqueous extract at a dose of 200 mg/kg orally in Wistar rats over 42 days. Toxicity assessments were conducted on days 14, 28, and 42. The results show that the Tikoni tea aqueous extract does not significantly reduce body weight gain and the growth of certain vital organs. However, liver and lung weights in males, and liver and spleen weights in females, decreased significantly. This extract decreased platelet counts in both sexes and significantly increased leukocyte counts in males. ALT and ALP activities increased significantly in males, while in females, AST, ALT, and ALP activities decreased significantly, and blood glucose levels...
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Posted by admin on Feb 28, 2026 in |
Millets are ancient small-seeded cereal crops that have sustained human populations for thousands of years, particularly in the arid and semi-arid regions of Asia and Africa. This review highlights the historical importance, domestication, cultural relevance, agro-biodiversity, nutritional value, and contemporary significance of millets and pseudo-millets in food systems. Millets are recognized for their drought tolerance, climate resilience, and suitability for low-input agricultural systems, making them valuable crops under changing environmental conditions. The review also discusses their superior nutritional profile, including dietary fibre, essential minerals, bioactive compounds, and low glycemic index, which support their role in addressing malnutrition, hidden hunger, and lifestyle-related disorders. In addition, the article examines the applications of millets in food technology and nutraceutical product development, such as bakery products, fermented foods, gluten-free formulations, dietary supplements, and fortified foods. Policy support, value-chain development, and renewed global attention, especially during the International Year of Millets 2023, have further strengthened the relevance of these crops. Overall, the review emphasizes that millets represent not only a link to traditional agriculture...
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Posted by admin on Feb 28, 2026 in |
The present study evaluates the antidiabetic potential of hydroalcoholic extracts derived from the fruit and peel of Ananas comosus (pineapple). Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia resulting from impaired insulin secretion or action. Natural plant-based remedies have gained attention for their efficacy and minimal side effects. The hydroalcoholic extracts were prepared using standardized extraction methods and subjected to phytochemical screening to identify bioactive constituents. The antidiabetic activity was assessed using in-vivo models of diabetes induced in experimental animals. Blood glucose levels and body weight were monitored throughout the treatment period. Results demonstrated a significant reduction in fasting blood glucose levels and improvement in lipid profile in animals treated with both fruit and peel extracts, with peel extract exhibiting comparatively higher efficacy. The findings suggest that Ananas comosus hydroalcoholic extracts possess promising antidiabetic properties, potentially attributable to their rich phytochemical content, including flavonoids, phenolics, and enzymes. These results warrant further studies to isolate specific active compounds and elucidate underlying mechanisms for clinical application in diabetes...
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Posted by admin on Feb 28, 2026 in |
Background and Aim: Phenanthrene is an aromatic compound with three benzene rings forming the main structure. It represents the majority of polycyclic aromatic hydrocarbons found in the environment and is found in a variety of areas including, burnt smoky coal particles soil and sediment, diesel emissions, tobacco and food smoke. The aim of the study was to determine the effect of phenanthrene on oxidative stress markers in male Wistar rats. Methodology: Fifty healthy rats weighing between 100 and 180g were used for this study. The animals were randomly assigned into five groups of ten rats per group. Group A served as control and the animals were administered with 1ml of DMSO oil only orally for three weeks. Groups B animals were administered orally with 5mg/kg of phenanthrene dissolved in 9ml of DMSO oil and Group C animals were administered orally with 10mg/kg of phenanthrene dissolved in 13ml of DMSO oil for three weeks. Group D animals, had 180mg/kg of phenanthrene dissolved in 1ml of DMSO oil orally, once, while...
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