Posted by admin on Feb 28, 2023 in |
The present study aimed to investigate the essential oil of Solenostemon monostachyus aerial part extract and its antioxidant and phytochemical potency. The essential oil of S. monostachyus aerial part was obtained by hydrodistillation using Clevenger-type apparatus, and the aqueous extract by infusion. Gas chromatography-mass spectrometry analysis of the essential oil gave twenty-two compounds as the major constituents with their retention factor. A total of forty-three compounds were identified of which limonene (55.40 %) and neral (10.39%) were found as major compounds followed by trans-verbenol (6.43%) and decanal (3.25%). The aqueous extract’s phytochemical analysis revealed terpenes, alkaloids, sterols, tannins, reducing sugar, flavonoids, saponins, and anthraquinones. HPLC analysis gave sixteen peaks, including tannins, caffeic acid, rutin, ferulic acid, morin, and apigenin. S. monostachyus exhibited antioxidant activity from the first dilution at 20 mg/mL up to the ninth dilution at 0.08 mg/mL in 2-fold dilutions signifying the presence of antioxidant compounds at those concentrations. Therefore, the results showed that the aqueous and hydroalcoholic extract of Solenostemon monostachyus exhibited antioxidant...
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Posted by admin on Feb 28, 2023 in |
Drug delivery via the oral mucous membrane is considered a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual means “under the tongue”, administrating substance via mouth so that the substance is rapidly absorbed via blood vessels under the tongue. The portion of the drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving acceptable bioavailability. Sublingual technology is convenient for dosing in geriatric, pediatric and psychiatric patients with dysphagia. Sublingual drug delivery shows fast therapeutic action than orally ingested drugs with fewer side effects. This review highlights advantages, disadvantages, different sublingual Gland, sublingual formulations such as tablets, films drops, sprays etc, and evaluation...
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Posted by admin on Jan 31, 2023 in |
Sapindus emarginatus Vahl. is extensively used in Indian traditional and folklore medicines to cure various human ailments. The preliminary phytochemical screening of the leaves revealed the presence of saponins, terpenoids, tannins, acids, flavonoids, cardiac glycosides, and sugars. Saponin applications were observed due to various biological, medicinal, and pharmaceutical actions. Several other uses for Sapindus have also been reported, such as making arrows from wood and decorative objects from seeds. The presence of saponin glycosides in the plant parts produces many beneficial pharmacological actions. These Sapindus drugs contain different active constituents, which various methods of extraction and separation methods can isolate. The choice of extraction procedure depends on the nature of the plant material and the components to be isolated. Maceration extraction, Soxhlet extraction, and microwave-assisted extractions give the most effective extraction of saponins from Sapindus species. Hence, this present review article provides detailed information about the different isolation procedures of saponin...
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Posted by admin on Jan 31, 2023 in |
The expansion of research on finding herbal sources for producing new effective and safe medicinal herbal remedies is an urgent pharmacy task. One of the ways to increase the amount of herbal medicinal preparations is a broad study of the pharmacological action of non-pharmacopoeial medicinal plants used in folk medicine. One of these plants is Black root officinalis (Cynoglossum officinale), which grows wild in the European part of Russia, Siberia, Central Asia, and the Caucasus, including North Ossetia, but does not form significant thickets. Today Cynoglossum officinale is used mainly in folk medicine as an anti-inflammatory, analgesic, sedative, and expectorant. When applied externally, Cynoglossum exhibits antipruritic properties and is capable of tissue regeneration. Therefore, the pharmacognostic study for further research on pharmacological effects on the human body is quite...
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