CHROMATOGRAPHIC ANALYSIS AND ANTIOXIDANT ACTIVITIES OF THE AERIAL PART ESSENTIAL OIL OF SOLENOSTEMON MONOSTACHYUS (P. BEAUV)Abstract
The present study aimed to investigate the essential oil of Solenostemon monostachyus aerial part extract and its antioxidant and phytochemical potency. The essential oil of S. monostachyus aerial part was obtained by hydrodistillation using Clevenger-type apparatus, and the aqueous extract by infusion. Gas chromatography-mass spectrometry analysis of the essential oil gave twenty-two compounds as the major constituents with their retention factor. A total of forty-three compounds were identified of which limonene (55.40 %) and neral (10.39%) were found as major compounds followed by trans-verbenol (6.43%) and decanal (3.25%). The aqueous extract’s phytochemical analysis revealed terpenes, alkaloids, sterols, tannins, reducing sugar, flavonoids, saponins, and anthraquinones. HPLC analysis gave sixteen peaks, including tannins, caffeic acid, rutin, ferulic acid, morin, and apigenin. S. monostachyus exhibited antioxidant activity from the first dilution at 20 mg/mL up to the ninth dilution at 0.08 mg/mL in 2-fold dilutions signifying the presence of antioxidant compounds at those concentrations. Therefore, the results showed that the aqueous and hydroalcoholic extract of Solenostemon monostachyus exhibited antioxidant activity.
Samuel Ehiabhi Okhale *, Chinyere Imoisi, Samuel Sunday Ode, Josiah Gana James and Akeem Lateef
Department of Medicinal Plant Research & Traditional Medicine, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P.M.B. 21 Garki, Abuja, Nigeria.
05 January 2023
15 February 2023
27 February 2023
28 February 2023