REVIEW-SUBLINGUAL ROUTE FOR SYSTEMIC DRUG DELIVERY
AbstractDrug delivery via the oral mucous membrane is considered a promising alternative to the oral route. Sublingual route is a rapid onset of action and better patient compliance than orally ingested tablets. Sublingual means “under the tongue”, administrating substance via mouth so that the substance is rapidly absorbed via blood vessels under the tongue. The portion of the drug absorbed through the sublingual blood vessels bypasses the hepatic first‐pass metabolic processes giving acceptable bioavailability. Sublingual technology is convenient for dosing in geriatric, pediatric and psychiatric patients with dysphagia. Sublingual drug delivery shows fast therapeutic action than orally ingested drugs with fewer side effects. This review highlights advantages, disadvantages, different sublingual Gland, sublingual formulations such as tablets, films drops, sprays etc, and evaluation parameters.
Article Information
1
228-235
484 KB
228
English
IJP
Jaini K. Patel *, Het Patel, Divykant Patel, Ghanshyam Patel, Priyanka Yadav and Dhruvi Panchal
Department of Pharmaceutics, Sharda School of Pharmacy, Pethapur, Gandhinagar, Gujarat, India.
pateljainipharma22@gmail.com
29 January 2023
15 February 2023
27 February 2023
10.13040/IJPSR.0975-8232.IJP.10(2).228-35
28 February 2023
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