Posted by admin on Aug 31, 2019 in |
Growing burden of degenerative metabolic diseases can be addressed with help of traditional and folkloric medicine. The purpose of this study is to evaluate an ethanolic defatted extract (EDE) of Cipadessa baccifera (CB) leaf for anti-diabetic wound healing activity in male albino Wistar rats. The defatted and non-defatted extracts were prepared using water and ethanol solvent system. They were evaluated for pharmacognostic study, wound healing activity using animal excision and incision models. Antioxidant activity was performed using DPPH assay. Ascorbic acid was used as reference standard for determination of antioxidant activity. The antimicrobial activity was also carried out by disc diffusion and well diffusion method using chloramphenicol as reference standard. The EDE of leaf showed higher total phenolic content. It was found to be 389.2 mg gal/l. These extract showed good DPPH radical scavenging activity, which was found to be 68.75% in comparison with ascorbic acid. This extract also showed a good zone of inhibition with disc diffusion and well diffusion method. On 16th day, the 200 mg/kg EDE...
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Posted by admin on Aug 31, 2019 in |
Plants have a long history as therapeutic tools in the treatment of human diseases and have been used as a source of medicines for ages. In search of new biologically active natural products, many plants and herbs used in traditional medicine are screened for natural products with pharmacological activity. Qinghao is a traditional Chinese medicine prepared from the aerial parts of Artemisia annua L. which belongs to Compositae family. It is used as an anti-parasitic and fever relieving agent. Artemisinin was isolated from Qinghao as a major bioactive constituent and has been used to treat malaria. Besides artemisinin, the chemical constituents of Qinghao include volatile oil, terpenes, flavonoids, and coumarins. Scopoletin-derived sesquiterpene ethers Sesquiterpene derivatives of 7-hydroxy-6-methoxycoumarin (Scopoletin) are not so common. The aim of the study was to investigate chemical constituents present in the leaves of Artemisia annua after the commercial extraction process of the plant for artemisinin. From the preliminary studies, the compound identified was found to be a coumarin- Scopoletin. The residual leaves were used for...
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Posted by admin on Aug 31, 2019 in |
Piper betel Linn. an important species of the Piperaceae family is an evergreen and perennial creeper, with glossy heart-shaped leaves that are magnificent reservoirs of phenolic compounds with anti-proliferative, anti-mutagenic, antibacterial and antioxidant properties. Phytochemical studies show that Piper betel contains a wide variety of biologically active compounds whose concentration depends on the variety of the plant species. Many research studies on Piper betel has reported that it contains important chemical constituents such as chavibetol, chavibetol acetate, caryophyllene, allylpyrocatechol diacetate, campene, chavibetol methyl ether, eugenol, a-Pinene, f-Pinene, u-Limonene, safrole, 1-8-cineol, and allylpyrocatechol monoacetate. These components are valued as a stimulant for its medicinal properties like anti-fungal, anti-nociceptive, anti-cancer, immunomodulatory, anti-halitosis, anti-diabetic, gastroprotective, anti-allergic, anti-fertility, anti-filarial, anti-larvicidal, wound healing and anti-dermatophytic. The present review is an attempt to highlight various traditional uses as well as pharmacological reports on Piper betel...
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Posted by admin on Jul 31, 2018 in |
Herbal formulation is a dosage form consisting of one or more herbs or processed herbs(s) in specified quantities to provide specific nutritional, cosmetic benefits, and/or other benefits meant for use to diagnose treat, mitigate disease of human beings or animals and / or to alter the structure or physiology of human beings or animals. The world health organization (WHO) estimates that 80% of the population (Asian and African countries) presently use herbal medicine for some aspect of primary health care. The present work was designed to evaluate the phytochemical potential and qualitative analysis of Ashwagandha churna. It was a simple maceration technique of extraction was followed to get the purified drug for further investigations. The chemical test was evaluated for the detection of different constitute include alkaloid, starch, flavonoid, tannins, saponins, steroid, carbohydrates, phenol, glycoside, terpenoids, resins, cardiac glycoside, coumarins. The qualitative study investigation includes HPLC and TLC. The result demonstrated the successful presence of above...
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Posted by admin on Jul 31, 2018 in |
The present study was carried out to evaluate the wound healing potential of different extracts of Oroxylum indicum leave in two different types of wound models in albino rats viz., incision and excision, and compare the effects with povidone iodine ointment which is used as standard drug. Among all the extract, the ethanolic extract at a dose of (250 mg/kg) possesses a significant increase in wound contraction and formation of scar in an excision wound model. The extract showed a significant increase in the breaking strength of resutured incision wound as compared to the control group (p<0.05). The result of the present study indicates that ethanolic extract of O. indicium has more significant wound healing property than the other two extracts in excision and incision wound...
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