Posted by admin on Aug 31, 2022 in |
Background: The current study was conducted at the department of veterinary pharmacology and toxicology to assess the impact of Emblica officinalis on oxidative stress produced by sub-acute enrofloxacin exposure in albino rats. Methodology: Albino rats weighing 200-300 grams were given enrofloxacin and Emblica officinalis orally through gavage needle. Blood samples were taken via capillary tube on the 28th day of the experiment and analyzed using laboratory procedures. Result: Sub-acute treatment of enrofloxacin at doses of 5 mg/kg b.wt. and 10 mg/kg b.wt. generated oxidative stress in rats, as evidenced by substantial changes in oxidative parameters, and affected liver and kidney functions, as seen by changes in biochemical markers of liver and kidney function. Emblica officinalis aqueous extract (200 mg/kg b. wt.) effectively reduces oxidative stress and changes in hepatic and renal function caused by enrofloxacin. Conclusion: Emblica officinalis (Amla) has antioxidant properties and can reduce oxidative stress caused by enrofloxacin in albino rats following sub-acute...
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Posted by admin on Aug 31, 2021 in |
Herbal medicines are widely used since time immemorial indicating that herbs are a growing part of modern, high-tech medicine. Current advancement in drug discovery technology and search for novel chemical diversity have intensified the efforts for exploring lead from “Ayurveda” the traditional system of medicine in India. Achyranthes aspera Linn. (Amaranthaceae) has been important coniferous plant in ayurvedic and indigenous medicinal systems. The medicinal plants are used for treatment of various diseases because of their safety and effectiveness. The problem of microbial resistance is growing and the outlook for the use of anti-microbial drugs in the future is still uncertain. The Clinical trials and animal research support the use of Achyranthes aspera for anti-inflammatory, anti-malarial, anti-ulcer genic, treatment of emotional stress and trauma, anti-microbial, insecticidal, fungicidal, asthma. Though almost all of its parts are used in traditional systems of medicines, seeds, roots and shoots are the most important parts which are used medicinally. The present review describes some of the important medicinal properties of Achyranthes aspera, which are instrumental...
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Posted by admin on Aug 31, 2021 in |
Natural plant products have been used throughout human history for many purposes. Dalbergia sissoo is also an herbal medicinal plant that belongs to the family Fabaceae (Leguminosae). Therefore, the aim of the present review is an effort to give a detailed survey of the literature on its traditionally medicinal use, morphology, phytochemistry, and pharmacological activities of the plant Dalbergia sissoo. Dalbergia sissoo is traditionally used to treat various systemic diseases and disorders such as cardiac diseases, gastrointestinal related disorders and diseases, sexual diseases, and skin diseases. It contains many active constituents, i.e., flavonoids, alkaloids, glycosides, carbohydrates, tannins proteins, fatty acids, and amino acids, useful in treating various types of diseases. Plant part extracts from Dalbergia sissoo are reported on anti-inflammatory, anti-termite, anti-diabetic, analgesic and antipyretic, anti-helminthic, antioxidant, antimicrobial, antinociceptive, osteogenic, anti-spermatogenic, gastroprotective, neuroprotective, anti-molluscicidal, anti-larvicidal, antiulcer, immunomodulatory, antibacterial activity are revealed in this review...
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Posted by admin on Aug 31, 2021 in |
Tinospora cordifolia (Gulvel) is traditionally used in ayurvedic medicine for apparently much varied conditions. It is commonly used in combination with other substances or sometimes alone. Supportive evidence from pharmacological studies suggests its prominent role in immune-modulation in conditions like diabetes mellitus, obstructive jaundice, and hepatic and splenic injury. Antioxidant, radioprotective, antihyperglycemic, anti-inflammatory, antiulcer and antispasmodic properties and capacity to dissolve urinary calculi also have supportive evidence. It is a potential antidepressant and enhances cognition and memory. Immune- modulation, preventing oxidative damage, and relieving inflammation are likely explanations for benefits in infections, joint inflammation, and allergies. The constellation of various activities plays a role in its protective effects against antitubercular and cytotoxic drugs, and toxins. It is helpful in potentiating other substances in the form of simple extraction. This review discusses its formulations, the relevance of supportive evidence and possible mechanisms of actions for its claimed benefits, and future...
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Posted by admin on Aug 31, 2021 in |
Lantana camara is a plant from the family- Verbenaceae. It is found in many states of India, mostly in Jammu-Kashmir, Himachal Pradesh, Tamil Nadu, South India, Uttar Pradesh and various parts of Maharashtra and other countries also. Mainly in disturbed areas, which include roadside, railway tracks, and canals. It is an ornamental plant but,in ancient times, it was used traditionally. The plant has various traditional uses. Parts of plant extracts are used traditionally like the healing of wounds, cuts, skin itches, eczema. The plant containing many more phytoconstituents like alkaloids, glycosides, saponins, steroids, terpenoids, carbohydrates, flavonoids, coumarins, etc. It has various pharmacological activities antioxidant, anti-microbial, antibacterial, antifungal, antiulcerogenic, anthelmintic, anti-hyperglycemic, anti-inflammatory, analgesic, anti-cancer, antitubercular, etc. It also has mosquito larvicidal activity. This review article was written by the study of many research and review articles from 1956 to March 2021 in which 72 articles were cited. This article reviewed various phytochemicals present in L. camara. The review draws attention to the traditional uses, analytical work, pharmacological activities and toxicology...
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