Posted by admin on Feb 1, 2014 in |
A series of substituted acetophenones are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized by using volumizer-Haack reaction to give new pyrazole derivatives. All the compounds 4a, 4b, 4c, 4d, 4e were screened for antioxidant, anti-inflammatory activity. Few of the compounds showing good antioxidant and anti-inflammatory...
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Posted by admin on Feb 1, 2014 in |
Adhataoda vasica and Ailanthus excelsa are distributed throughout tropical and subtropical parts of India. Their leaves are used as expectorant and bronchodilator. The present investigation deals with the comparative pharmacognostical study of the leaves of the two species and establishment of its quality parameters. Detailed morphological and qualitative as well as the quantitative microscopic study was carried out. Phytochemical screening of the species followed this. Leaf surface microscopy of Adhataoda vasica shows polygonal thin walled epidermal cells and diacytic stomata whereas Ailanthus excels shows penta and hexagonal epidermal cells and anomocytic stomata. The chief powder characteristics of Adhataoda vasica leaf powder are 2-4 celled blunt covering trichomes, sessile-glandular trichomes, acicular and prismatic calcium oxalate crystals whereas Ailanthus excelsa leaf powder shows multicellular bent thick walled covering trichomes, multicellular head and stalk glandular trichomes, cluster and rosette calcium oxalate crystals. The present work can serve as a useful tool in the identification, authentication, and standardization of the plant material and distinguishing the two species from each other. The present study...
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Posted by admin on Feb 1, 2014 in |
Callicarpa macrophylla (Verbenaceae) has been commonly used in traditional medicine for a wide range of ailments related to the circulatory, digestive, endocrine, respiratory and skeletal systems as well as to infectious diseases. It provides the up-to-date information that is available on the botany, traditional uses, phytochemistry, pharmacology, and toxicology of Callicarpa macrophylla. Additionally, to highlight the possible uses of this species to treat different diseases and to provide a basis for future research. The information was collected from scientific journals, books, theses, and reports via a library and electronic search (Google Scholar, Web of Science and Science Direct). The phytochemical studies have shown the presence of many secondary metabolites belonging to terpenoids, flavonoids, carbohydrate, lignans, phenols, and sterols. Crude extracts and isolated compounds from Callicarpa macrophylla show a wide spectrum of pharmacological activities, such as anti-diabetic, anti-inflammatory, antifungal, antibacterial, anti-arthritic, anti-pyretic & analgesic activities, as well as a usefulness help in alleviating pain in rheumatism. Callicarpa macrophylla has been a widely used a source of medicine for years without...
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