Posted by admin on Dec 1, 2014 in |
Amino acids are biologically active substances, and a number of them are essential for living beings. Amino acids are found in living cells as well as in body fluids of higher animals, in amounts, which vary according to the tissue and particular amino acid. Amino acid analysis refers to the methodology used to determine the amino acid composition or content of proteins, peptides, and other pharmaceutical preparations. Proteins and peptides are macromolecules consisting of covalently bonded amino acid residues organized as a linear polymer. The sequence of the amino acids in a protein or peptide determines the properties of the molecule. Proteins are considered large molecules that commonly exist as folded structures with a specific conformation, while peptides are smaller and may consist of only a few amino acids. Amino acid analysis can be used to quantify protein and peptides, to determine the identity of proteins or peptides based on their amino acid composition, to support protein and peptide structure analysis, to evaluate fragmentation strategies for peptide mapping, and...
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Posted by admin on Dec 1, 2014 in |
Simarouba glauca is one of the important herbal drugs used against dysentery and has a long history in herbal medicine in many countries. The bark and leaf extract of Simarouba is well known for its different types of pharmacological properties such as hemostatic, antihelminthic, antiparasitic, antidysenteric, antipyretic and anti-cancerous. The bark is used to cure fever, malaria, stomach and bowel disorders, haemorrhages, amoebiasis as well as leaf, fruit pulp and seeds are possessing medicinal properties such as analgesic, antimicrobial, antiviral, astringent emmenagogue, stomachic tonic, and vermifuge. The crushed seeds are used as Antigo against snake bites. The crude drug contents and active principles such as glaucarubin, quassinoids, ailanthinone, benzoquinone, holacanthone, melamine, simaroubidin, simarolide, simarubin, simarubolide, sitosterol. These are mainly involved in the pharmacological activities of this plant. The present review summarizes pharmacological, biotechnological, ethnobotanical phytochemical aspects as well as nursery practices of this medicinal...
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Posted by admin on Nov 1, 2014 in |
The current practice of medicine indebted much to the knowledge and achievements of the past. It is really surprising that far back Greco-Arab physicians were aware of the various diseases and scientifically mentioned them. Most of the knowledge is still in practice. Modern days practice relies on the fundamentals proposed by them. In the classical text of Unani Medicine, headache is described in detail. The Shaqeeqa (a migraine) is described nearly in all classical text of Unani medicine as a disease entity includes definition, etiopathology, clinical feature, and...
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Posted by admin on Nov 1, 2014 in |
The objective of this review is to update and assess the chemistry, composition, mechanism of action, pharmacokinetics, nutritional value and toxicology of garlic. The medicinal properties of garlic include immune functions, antibacterial activities, antifungal activities, antivirus activities, de-toxification, anti-oxidant agent, prevent platelet aggregation, reduction in blood pressure, lowering of cholesterol and triglyceride, prevention of arteriosclerosis, antithrombotic, anticancer effects. The scientific research shows that the wide variety of dietary and medicinal functions of garlic can be attributed to the sulfur compounds present in or produced from garlic. Chemical analysis of garlic cloves has revealed a concentration of sulfur-containing compounds (1-3%). Although garlic produces a large number of sulfide compounds from a few sulfur-containing amino acids, their functions are different from one another like allicin, diallyl, mono, di, tri, tetra, hexa and hepta sulfides, vinyldithiins and ajoenes., Allyl, propyl disulfide and other organic sulfide or sulfur compounds diallyl disulfide, allinase, alliin(S-allyl cysteine...
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Posted by admin on Nov 1, 2014 in |
Coccinia grandis Linn. Voigt, also known as Coccinia indica belongs to the family Cucurbitaceae. It is extensively used in traditional medicine for the treatment of leprosy, jaundice, asthma, bronchitis, skin eruptions, burns, tongue sores, earache, indigestion, eye infections, nausea, insect bites, and fever. Phytochemical studies reveal the presence of phenols, tannins, saponins, terpenoids, flavonoids, arabinose, xylose, mannose, galactose, glucose and rhamnose. Studies on the plant extract particularly the leaf extract shows that it possesses antihyperglycemic, xanthine oxidase inhibitory, analgesic, anti-inflammatory, and antipyretic, antioxidant, antihyperlipidemic, antimicrobial, anti-hepatotoxic and anti-insecticidal activities. Among these, the plant’s activity against diabetes has been extensively investigated. Current studies on its antioxidant activity reveal its potential in cancer therapy. The plant leaf extract also shows significant activity chemoprotective effect against cyclophosphamide, commonly used in the treatment of cancer and autoimmune diseases. A review of the various studies on the plant is provided to understand its medicinal...
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