Posted by admin on Feb 28, 2015 in |
Plants are valuable sources of natural products. Despite the availability of different approaches for the discovery of therapeutically, natural products remain as one of the best reservoirs of new structural types. They play a major role in the cure of various diseases from ancient time. Role of plant metabolites to inhibit the growth and activity of pathogenic bacteria is cherished. Research towards the invention of sources of plant metabolites gives sustenance against the problem of development of resistant pathogen. The review presents information about some new sources of phytometabolites against...
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Posted by admin on Feb 1, 2015 in |
The traditional Indian medicine – Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing properties. Wounds are the result of injuries to the skin that disrupt the soft tissue. Wound healing can be defined as a complex dynamic process results in the restoration of anatomic continuity and function. Various plant products have been used in the treatment of wounds over the years. Wound healing herbal extracts promote blood clotting, fight infection, and accelerate the healing of wounds. Hence in the current review, a list of the plants used in traditional medicine for the treatment of wounds was screened. It is a beneficial work for researchers to provide many details about the wound healing herbs and development of safe and effective and globally accepted herbal drugs for cuts and...
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Posted by admin on Feb 1, 2015 in |
Peptic Ulcer Disease (PUD) is an inflammation along the mucosal lining of esophagus, stomach or duodenum or anywhere in the gastrointestinal tract. PUD is the most common gastrointestinal disorder in clinical practice because of alteration in lifestyle and food habits. The main symptoms related to PUD are Indigestion, heartburns, burning pain or abdominal pain, nausea, vomiting, constipation, bloating of stomach and abdomen, not feeling of well in both body and mind. In severe cases, symptoms can be dark or black stool (due to bleeding), vomiting blood (look like “coffee-grounds”), Weight loss, and severe pain in the mid to upper abdomen. The most important complications are Hemorrhage, Bleeding, Perforation (a hole through the wall of the stomach), Gastric outlet obstruction, if not treated properly. The drugs like Antacids, H2 Receptor antagonist and Proton pump inhibitors are used for PUD all around world widely to relieve the symptoms by the allopathic medicine side. Many of Medicinal plants are used for their anti-ulcer, anti-secretory & Gastro-protective property by the practitioners of herbal...
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Posted by admin on Dec 1, 2014 in |
Cocoa and chocolate can also be rich sources of flavonoids. Flavanols isolated from cocoa exhibit strong antioxidant properties in-vitro. Flavanol-rich cocoa and chocolate increased plasma antioxidant capacity and reduced platelet reactivity. Flavonoids are phenolic substances isolated from a wide range of vascular plants, almost over 8000 individual compounds known. They act in plants as antioxidants. Many studies have suggested that flavonoids exhibit biological activities, including antiallergenic, antiviral, anti-inflammatory, and vasodilating actions. Most interest has been devoted to the antioxidant activity of flavonoids, which is due to their capability to reduce the free radical formation and to scavenge free radicals. Most ingested flavonoids are extensively degraded to various phenolic acids, some of which still contain a radical scavenging ability. Both the absorbed flavonoids and their metabolites may display an in-vivo antioxidant activity. This review presents the current knowledge on structural aspects of most common flavonoids as in-vivo antioxidant and their effects on platelets, bioavailability, and cardiovascular...
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Posted by admin on Dec 1, 2014 in |
Moxifloxacin is a broad-spectrum antibiotic. Moxifloxacin is a 4th generation fluoroquinolone. Chemically it is 8-methoxy-fluoroquinolone. It acts by inhibiting DNA gyrase, a type topoisomerase II and topoisomerase IV. These are enzymes which are necessary for separation of bacterial DNA, so inhibits the replication of the cell. Its study was based on single-drug delivery, intravenous. The apparatus which have been used is a reversed-phase Li Christopher RP-18 with a column and a mobile phase comprising different solvents. Fluorescence detection was carried out at a higher wavelength of 290 nm and an emission wavelength of 550 nm. This method causes a short retention time (8.0 min) for moxifloxacin. The linear curves were obtained from 5-250 μg/L in plasma and from 0.1-2.5 μg/g of brain tissue. Limit of quantification (LOD) was 5 μg/L in plasma and 0.1 μg/g in brain tissue. The method causes the detection of systemic antimicrobial agents in plasma and CNS of infected mice by Listeria...
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