Posted by admin on May 17, 2016 in |
The hypolipidemic activity of Aloe vera (Family: Liliaceae) extract has been studied in two models of hyperlipidemia in rats. In an acute model, hyperlipidemia was induced by injecting a single dose of triton WR-1339 (400mg/kg, b.w.) intraperitoneally in rats. Feeding with Aloe vera extract at the dose of 500 mg/ kg, b.w. exerted a significant lipid-lowering effect as assessed by the reversal of plasma levels of total cholesterol (TC), phospholipids (PL), triglyceride (TG) and reactivation of post-heparin lipolytic activity (PHLA). In the chronic model, hyperlipidemia was induced by feeding with cholesterol-rich- HFD in rats. The treatment with seeds extracts of Aloe vera (500 mg/ kg b.w) simultaneously for 15 days also caused lowering of lipid levels in plasma and liver following reactivation of plasma post-heparin lipolytic activity and hepatic lipoprotein lipase activity in animals. The hypolipidemic activity of Aloe vera was compared with a standard drug guggulipid (200 mg/ kg, b.w.) in both...
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Posted by admin on Dec 1, 2014 in |
Amino acids are biologically active substances, and a number of them are essential for living beings. Amino acids are found in living cells as well as in body fluids of higher animals, in amounts, which vary according to the tissue and particular amino acid. Amino acid analysis refers to the methodology used to determine the amino acid composition or content of proteins, peptides, and other pharmaceutical preparations. Proteins and peptides are macromolecules consisting of covalently bonded amino acid residues organized as a linear polymer. The sequence of the amino acids in a protein or peptide determines the properties of the molecule. Proteins are considered large molecules that commonly exist as folded structures with a specific conformation, while peptides are smaller and may consist of only a few amino acids. Amino acid analysis can be used to quantify protein and peptides, to determine the identity of proteins or peptides based on their amino acid composition, to support protein and peptide structure analysis, to evaluate fragmentation strategies for peptide mapping, and...
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Posted by admin on Sep 1, 2014 in |
Amino acids are biologically active substances, and a number of them are essential for living beings. Amino acids are found in living cells as well as in body fluids of higher animals, in amounts, which vary according to the tissue and particular amino acid. Amino acid analysis refers to the methodology used to determine the amino acid composition or content of proteins, peptides, and other pharmaceutical preparations. Proteins and peptides are macromolecules consisting of covalently bonded amino acid residues organized as a linear polymer. The sequence of the amino acids in a protein or peptide determines the properties of the molecule. Proteins are considered large molecules that commonly exist as folded structures with a specific conformation, while peptides are smaller and may consist of only a few amino acids. Amino acid analysis can be used to quantify protein and peptides, to determine the identity of proteins or peptides based on their amino acid composition, to support protein and peptide structure analysis, to evaluate fragmentation strategies for peptide mapping, and...
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Posted by admin on Apr 1, 2014 in |
The poisonous and medicinal plants are found in a natural ecosystem. The Arisaema murrayi (Hook) is an herb which is highly poisonous. It is found in the hilly region of Mumbai area. Livestock, cattle and human beings do not consume fruits and tubers of the plant, so the forensic study of this plant is carried out. Aqueous extracts of tuber 2%, 4% and 6% feed orally to Swiss albino mice. Present investigation study includes the histopathology, phyto-chemistry and quantitative microscopy. It is observed that liver, intestine, and kidney were severally damaged by using the Arisaema murrayi (Hook) plant parts. The forensic study proved that these organs were damaged by the poison of Arisaema murrayi (Hook) plant of the...
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Posted by admin on Jan 1, 2014 in |
Calotropis gigantea (Asclepiadaceae) is a perennial herb with a long history of use in traditional medicines. A wide range of chemical compounds including cardiac glycosides, flavonoids, terpenoids, alkaloids, tannins, & resins has been isolated from this plant. The plant has been used for various disease condition including leprosy, ulcers, tumors and piles. Various pharmacological activities reported like analgesic activity, antipyretic activity, pregnancy interceptive activity, CNS activity, anti-inflammatory activity, procoagulant activity, anti-diarrhoeal activity, free radical scavenging activity, antimicrobial activity, anti-tumor activity, antifungal activity, antitussive activity, and antifeedant...
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