Posted by admin on Apr 29, 2015 in |
Butea monosperma var. lutea, a native of India, is commonly known as “Palash” and popularly known as “Flame of Forest.” Traditionally it has been found that flowers have antimicrobial, wound healing, antifungal, antidiarrhoeal, hypoglycemic, hepatoprotective, antioxidant, anthelmintic, anti-convulsive, antistress, antidiabetic, anti-inflammatory activity. In the present study, crude hydroalcoholic flower extract was examined for anticancer activity. To determine in-vitro anticancer activity, different concentrations of crude extract were tested on MCF-7 breast cancer cell line by 3-(4,5-dimethyl thiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The extract showed significant antiproliferative activity and a dose-dependent effect. Minimum inhibition 16.8% was shown by extract at concentration 62.5 µg/ml and maximum inhibition (46.89%) observed at 500 µg/ml. The flower extract showed activity in the potential range for further investigation of cancer cells....
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Posted by admin on Apr 29, 2015 in |
Phytochemicals are the best remedies to all kind of diseases and disorders throughout the world. There are a lot of plants, and its sources are playing a role as a heart, liver and kidney savers. In our present investigation, the famous fruit tree Annona squamosa (Annonaceae) leaves extract used for the hepatoprotective activity. The phytochemicals present in the aqueous leaves extracts were analyzed using preliminary biochemical analysis, and functional groups are characterized using Fourier Transform Infrared Spectrophotometer (FT-IR). The animals were divided into six groups, in that apart from the first group (normal control), five groups are induced with paracetamol (acetaminophen) with standard drug and two plant drug extracted by aqueous one is induced control. The increasing of enzymes and bilirubin, triglycerides and cholesterol and decreasing protein shows the liver damage. These levels are changed into normal range indicates efficiency of our plant drug. The histopathalogical results are also confirmed our hepatoprotective capability is...
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Posted by admin on Apr 29, 2015 in |
Rhizoma Curcumae longae is the dried rhizome of Curcuma longa L. (Zingiberaceae), commonly known as turmeric, has a long history of traditional uses for culinary purposes as a spice and as a food colorant. This study was aimed at establishing the microscopic identification of different commercial samples and developing parameters for discriminating turmeric powders. In this study, fifteen samples from different origins were analyzed, and each experiment was performed in triplicate. Statistical techniques were used to analyze the partition of the structure observations. The principal component analysis was applied to the distribution of the forty-five sample observations. In consequence, eleven discriminating structure features were identified. The most diagnostic features are yellow clumps of gelatinized starch, covering trichome, starch granules, vessels, cork, and fibers. The results showed that microscopic observation of rhizoma Curcumae longae powder could be grouped according to the presence of non-glandular trichome, and calcium oxalate crystals clusters. These findings revealed that microscopic analysis, coupled with statistical analysis, could provide a simple platform for medicinal plant identification, particularly for the...
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Posted by admin on Apr 29, 2015 in |
The present study was to investigate the antioxidant activity of aqueous bark extract of Spondias pinnata (Linn. f.) Kurz (Family: Anacardiaceae) in streptozotocin-induced diabetic rats. The antioxidant activity was evaluated by the activities of liver enzymes, antioxidant enzymes, and the extent of lipid peroxidation (LPO) in the liver of streptozotocin (STZ) ‑diabetic rats. S. pinnata extract decreased the LPO by 17%, activities of alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase decreased by 20%, 17% and 36% respectively (P<0.05). The liver reduced glutathione, activities of glutathione reductase, glutathione peroxidase, and glutathione S-transferase of plant extract treated diabetic rats were increased by 43%, 44%, 69% and 52% respectively (P<0.05). The light microscopic appearance of the liver tissue in S. pinnata treated rats has corroborated the biochemical results. The present investigation revealed that the bark extract of S. pinnata exerts significant in-vivo antioxidant activities in diabetic...
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Posted by admin on Apr 29, 2015 in |
Lymphatic filariasis (LF) is a major public health problem not only in India but also in other developed countries. Filariasis is the disease which is caused by a group of filarial worms. It is transmitted by mosquitoes – Culex quinquefasciatus globally the most important vector. They cause high morbidity and mortality among humans. The proper management is needed for preventing the morbidity and mortality by laboratory diagnostic methods. Ir-reversible ‘elephantiasis’ is the major clinical manifestation for LF. Diethylcarbamazine (DEC) is the drug of choice for treating lymphatic filariasis. Sequential gradient pump therapy and complete decongestive therapy (CDT) are some additional treatment for better therapeutic...
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