Posted by admin on May 31, 2026 in |
Background/Objective: Calamus tenuis Roxb. (family Arecaceae) is a climbing palm used in traditional medicine across South and Southeast Asia for treating fever, hemorrhoids, bacterial infections, inflammation, diabetes, and gastric complaints. Despite its ethnomedicinal importance, information on the thrombolytic potential of its leaves remains scarce. This study aimed to investigate the phytochemical composition, antioxidant capacity, and thrombolytic activity of the methanolic extract of C. tenuis leaves. Methods: Dried leaves were subjected to cold maceration in methanol for 15 days, and the crude extract was obtained by rotary evaporation. Qualitative phytochemical screening was performed using standard colorimetric tests. Antioxidant activity was assessed by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay using a natural logarithmic regression curve fit, and thrombolytic activity was evaluated by an ex-vivo clot lysis assay using streptokinase as the standard and distilled water as a negativecontrol. Results: Phytochemical screening confirmed the presence of alkaloids, carbohydrates, saponins, flavonoids, steroids, glycosides, and tannins. Natural logarithmic regression analysis optimized the evaluation of antioxidant capabilities, generating a precise fit line (y =...
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Posted by admin on May 31, 2026 in |
Citrus limon is the commonly available medicinal plant in India. Which is utilized for the various pharmacological and food activities. During this year, commercial production of lemons was approximately 4.3 million tons that harvested from 25734 hectares in Iran. Nowadays, the interest in essential oils and their application in food preservation have been amplified as the natural additives to improve the shelf-life and the safety of food products, due to the risk in using synthetic preservatives. Also, food-borne diseases are a growing public health problem worldwide, calling for more impressive preservation tactics. Lemon has many bioactive components such as citric acid, Ascorbic acid, minerals, flavonoids and essential oils. In present work Citrus limon leaves subjected for extraction and followed by phytochemical Investigation and antimicrobial activity. The result shows that Citrus limon leaves ethanolic extract showing significant antimicrobial activity. The antimicrobial activity of the plant extract will be beneficial for the treatment of various microbial diseases such as fungal infection, skin rashes, ringworm and other skin related...
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Posted by admin on May 31, 2026 in |
Thrombosis remains a leading cause of cardiovascular morbidity and death, with complications including myocardial infarction and stroke. It is characterized by the development of thrombi, or blood clots, inside blood vessels. Herbal remedies are increasingly being studied as safer, complementary alternatives to conventional thrombolytics like streptokinase. A human blood clot lysis model was used to investigate the in-vitro thrombolytic efficacy of two Bangladeshi polyherbal formulations, Rohitakarishta (Hepatolin) and Sharbat Chylosin (Hepa-10). Ten healthy people’s venous blood samples were placed under incubation at 37°C to cause clot formation. Thrombolytic activity of the formulations was evaluated at 100 µL and 200 µL concentrations using distilled water as the negative control and streptokinase as the positive control. The standard, streptokinase, showed maximum clot lysis (58.52% ± 2.02), while the negative control caused minimal clot lysis (2.8% ± 0.48). At 200 µL, Hepatolin caused the most clot lysis (51.52% ± 0.43), followed by Hepa-10 (42.30% ± 1.64). At 100 µL, the lysis rates of Hepatolin and Hepa-10 were (26.11% ± 2.09) and (24.36%...
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Posted by admin on May 31, 2026 in |
This experiment was conducted to determine in-vitro antidiabetic properties of Barleriagibsoni stem extracts based on the inhibition of α-amylase and uptake of glucose by yeast cell models. At varying concentrations, ethanol and aqueous extracts were evaluated and compared to the standard drug Metformin. The two extracts showed a concentration dependent rise in activity, but the ethanol extract always proved to have better inhibitory effects than the aqueous extract. The ethanol extract and the aqueous extract had 75.18 and 64.21% inhibition, respectively, in the glucose uptake assay, as compared to 87.10% inhibition of metformin. It is noteworthy that the ethanol extract had an activity of about 86% of the standard drug, and could be observed with a reasonable activity even at lower levels. The two extracts were moderate in the α-amylase inhibition assay, although the ethanol extract was more effective. Comparative analysis revealed that the ethanol extract was more effective in both assays implying that it is effective in extracting bioactive compounds like flavonoids, phenolics and alkaloids. Moreover, more pronounced...
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Posted by admin on May 31, 2026 in |
The National AIDS Control Programme (NACP) has been a cornerstone of India’s comprehensive, technology-driven strategy to address non-communicable diseases, maternal health, and mental health since the country’s independence. Phase V of NACP (2021–2026) seeks to eradicate HIV/AIDS as a public health threat by 2030 through a rights-based, inclusive approach, and this overview looks at how the NACP has changed and what impact it has had on the country’s public health. The paper addresses the pathogenesis, transmission, and treatment of HIV, highlighting India’s considerable epidemiological successes: a 49% reduction in new infections and an 80% fall in AIDS-related deaths between 2010 and 2026. Key to these breakthroughs is the merging of modern medical and digital advancements, including: Medical Breakthroughs: The creation of low-cost, generic versions of long-acting injectables like Lecavalier for pre-exposure prophylaxis (Prep). Digital Transformation: The implementation of the Strategic Information Management System (SIMS) for real-time tracking and the spread of telemedicine for antiretroviral medication (ART)...
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