Posted by admin on Feb 28, 2025 in |
The fruit, native to Central America, is known for its unique appearance and rich nutritional content. This profile includes an examination of the plant’s macroscopic and microscopic features of fruit anatomy. A significant focus is placed on the phytochemical constituents of Canistel, which include alkaloids, flavonoids, tannins, and terpenoids. These compounds associated with various biological activities. The bioactive substances contribute to the plant’s antioxidant property suggesting its therapeutic potential in traditional medicine. Also the plant’s role in managing conditions like diabetes, hypertension, and digestive disorders has been documented in traditional medicine. The pharmacognostic profile also includes the plant’s pharmacological properties, which support its use in the development of natural health products. The canistel is egg-shaped fruit and sweet, dense pulp Microscopically, the plant’s cellular structures, such as Parenchyma cells, Vascular Tissues, Fibres and vascular bundles, This detailed anatomical study helps in ensuring the authenticity and quality of the plant material used in medicinal applications. The plant’s medicinal uses also support its potential therapeutic value, as it has been utilized...
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Posted by admin on Feb 28, 2025 in |
Natural plant extracts have gained interest in cancer research due to their potential therapeutic properties. This study investigates the in-vitro cytotoxic effects and phytochemical composition of Mammea africana stem bark and Calophyllum inophyllum leaves methanol extracts against H460 lung cancer cells using the MTT assay, with 5-Fluorouracil (5FU) as a standard control. Phytochemical screening revealed that M. africana had high terpenoid content and moderate levels of flavonoids, tannins, and phenolics, while C. inophyllum had higher flavonoid and phenolic content, moderate saponins and terpenoids, and lower tannins and alkaloids. The extraction yields were 12.5% w/w for M. africana and 9.8% w/w for C. inophyllum. Cytotoxicity analysis demonstrated that M. africana exhibited strong cytotoxic effects, with an IC₅₀ value of 2.60 µg/mL, comparable to 5-Fluorouracil (IC₅₀ = 2.71 µg/mL), while C. inophyllum showed moderate cytotoxic activity (IC₅₀ = 30.00 µg/mL). The cytotoxic effects were dose-dependent, with M. africana achieving 97.47% cytotoxicity at 100 µg/mL, whereas C. inophyllum reached 85.4% at the same concentration. The findings suggest that the potent cytotoxic effects of Mammea africana could be attributed to its high terpenoid and tannin content, whereas the moderate activity of C. inophyllum may be linked...
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Posted by admin on Feb 28, 2025 in |
Tinospora cordifolia (Giloy), has been utilized across Ancient Indian and Ayurvedic medication for centuries due to its significant pharmacological properties. This comprehensive review explores the botanical, chemical, and therapeutic aspects of T. cordifolia, highlighting its widespread distribution, detailed plant description, and various vernacular names. The plant’s cultivation preferences, climate and soil requirements, and propagation methods are examined. Additionally, the review delves into the plant’s medicinal potential, particularly its antiviral and immunomodulatory properties, which acquired prominence during COVID-19. Active compounds such as glycosides, steroids, diterpenoid lactones, and alkaloids contribute to its pharmacological efficacy. T. cordifolia enhances the host immune system, promotes skin health, and offers anti-aging benefits. While generally safe, precautions for certain conditions like diabetes and pregnancy are advised. This review underscores T. cordifolia’s role in modern herbal medicine and its potential for future pharmacological...
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Posted by admin on Feb 28, 2025 in |
Objectives: In Unani medicine the study of disease, known as Ilmul Amraz or Mahiyatul Amraz, holds a great importance as it lays the foundation for understanding the causes, development and ensuring accurate diagnosis. However, the literature on this subject is scattered across various manuscripts, necessitating collection and compilation of this valuable knowledge to deepen the understanding of disease frameworks within Unani medicine. The content in this article has been condensed from the original sources and is introduced in brief. Methods: The “input-processing-output” approach is used to carry out the planned literary research. The literature has been obtained from a variety of Reference books, Classical texts, academic works and digital formats. Conclusion: This review underscores the significant contributions of Unani physicians, presenting their original works, innovations, and practical experiences. The theoretical input of Unani physicians has played a key role in advancing the understanding of diseases and the processes behind...
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Posted by admin on Feb 28, 2025 in |
This research demonstrates the use of inductively coupled plasma-mass spectrometry (ICP-MS) following microwave digestion in the estimation of the quantity of iodine in pharmaceutical samples and herbal formulations. The samples were dissolved in 4 mL of a 2% Tetra-methyl-ammonium-hydroxide solution, and iodine was used as a reference standard. Collectively, the findings show that the method was linear with calibration curves ranging from 1 ppb to 100 ppb. The recoveries of the examined samples fell between 98 and 115%. The precision of repeatability for iodine concentration ranged from 2.11% to 2.85% for intermediate precision. The present method is robust according to the percentage of RSD of robustness test under various modified conditions. For herbal formulations and pharmaceutical samples, validated methods were proved to be applicable, sensitive, accurate, and...
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