Posted by admin on Aug 31, 2021 in |
Tinospora cordifolia (Gulvel) is traditionally used in ayurvedic medicine for apparently much varied conditions. It is commonly used in combination with other substances or sometimes alone. Supportive evidence from pharmacological studies suggests its prominent role in immune-modulation in conditions like diabetes mellitus, obstructive jaundice, and hepatic and splenic injury. Antioxidant, radioprotective, antihyperglycemic, anti-inflammatory, antiulcer and antispasmodic properties and capacity to dissolve urinary calculi also have supportive evidence. It is a potential antidepressant and enhances cognition and memory. Immune- modulation, preventing oxidative damage, and relieving inflammation are likely explanations for benefits in infections, joint inflammation, and allergies. The constellation of various activities plays a role in its protective effects against antitubercular and cytotoxic drugs, and toxins. It is helpful in potentiating other substances in the form of simple extraction. This review discusses its formulations, the relevance of supportive evidence and possible mechanisms of actions for its claimed benefits, and future...
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Posted by admin on Aug 31, 2021 in |
Lantana camara is a plant from the family- Verbenaceae. It is found in many states of India, mostly in Jammu-Kashmir, Himachal Pradesh, Tamil Nadu, South India, Uttar Pradesh and various parts of Maharashtra and other countries also. Mainly in disturbed areas, which include roadside, railway tracks, and canals. It is an ornamental plant but,in ancient times, it was used traditionally. The plant has various traditional uses. Parts of plant extracts are used traditionally like the healing of wounds, cuts, skin itches, eczema. The plant containing many more phytoconstituents like alkaloids, glycosides, saponins, steroids, terpenoids, carbohydrates, flavonoids, coumarins, etc. It has various pharmacological activities antioxidant, anti-microbial, antibacterial, antifungal, antiulcerogenic, anthelmintic, anti-hyperglycemic, anti-inflammatory, analgesic, anti-cancer, antitubercular, etc. It also has mosquito larvicidal activity. This review article was written by the study of many research and review articles from 1956 to March 2021 in which 72 articles were cited. This article reviewed various phytochemicals present in L. camara. The review draws attention to the traditional uses, analytical work, pharmacological activities and toxicology...
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Posted by admin on Jul 31, 2020 in |
Nowadays, the use of essential oils as alternative therapies has gained worldwide concern, owing to their various biological activities. Considerable attention has been devoted to essential oil, which is widely used for its important properties, including antimicrobial, anti-inflammatory, antispasmodic, cytoprotective, hepatoprotective, with strong antioxidant actions. Eucalyptol is an essential oil present in large amounts in a variety of plants, which is frequently used in the manufacture of cosmetics, to increase percutaneous penetration of drugs, as a nasal decongestant and anti-cough agent, and in aromatherapy. GC analysis of the essential oil was carried out on the Agilent 7820A system with a mass detector (MS) and a HP-5 MS column (30 m × 0.25 mm, 0.25 μm film thickness). Nineteen essential chemical constituents were identified based on GC-MS in Eucalyptus oil supplied from the pharmacy. The main constituents of Eucalyptus oil are eucalyptol (76.81%), γ -terpinene (7.75), α-pinene (6.62), and α-terpineol (1.44%). These four components account for 92.6% of the total relative content of the Eucalyptol oil. This research also demonstrated...
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Posted by admin on Jul 31, 2020 in |
Acne is a skin-related condition entailing many psychological complications. Although several medications have been developed, natural remedies attracted more attention because of the less side effects and multifunctional. The objective of this study was to prepare and evaluate the anti-acne effects of a pharmaceutical gel containing herbal extracts, including Lawsonia inermis and Matricaria chamomilla. The total phenolics of extracts were determined with the Folin-Ciocalteu method. Using Hydroxypropyl methylcellulose (HPMC), carboxymethyl cellulose (CMC) and propylene glycol (PEG), the pharmaceutical gel was formulated and the physical properties of the formulation were specified at 37 ± 2 °C. The release of the active ingredients from the optimum formulation was investigated using Franz cell device. The results showed that the optimum formulation was stable at least for 3 months. The total phenol content of the aqueous extract of Henna leaves, hydroalcoholic extract of chamomile flowers, and the optimum formulation was 57.8 mg/g ex, 181.08 mg/g and 202.75 mg/g, respectively. Nearly 80 % of the phenolic compounds in the optimum formulation were released over...
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Posted by admin on Aug 31, 2019 in |
The aim of this study was to identify the phytochemical groups of hydroethanolic leaf extract of Senna sieberiana DC and its fractions and to investigate their free radical scavenging activity. S. sieberiana leaves were extracted with a hydroethanolic solvent. From the hydroethanolic extract 3 fractions were obtained after a liquid/liquid fractionation (dichloromethane, ethyl acetate, and water). Phytochemical screening of the leaf extract and its fractions was done using standard reactions. Free radical scavenging activity was assessed using DPPH and ABTS assays. Tannins, flavonoids, anthracene derivatives, sterols, and triterpenoids were the main phytochemical constituents of the leaf extract and fractions. The hydro-ethanolic leaf extract of Senna sieberiana, its dichloromethane, ethyl acetate, and aqueous fractions and ascorbic acid had respective IC50 values of 191.6 ± 3.82; 495.73 ± 8.96; 165.8 ± 4.85; 50.40 ± 2.65; 19.53 ± 0.13 µg/ml in ABTS assay. In DPPH assay, the IC50 values were 44.8 ± 1.22; 218.93 ± 9.01; 32.13 ± 1.8; 26. 4 ± 0.11; 4.66 ± 0.07 µg/ml respectively for the leaf extract,...
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