Posted by admin on Jun 30, 2019 in |
Introduction: The objective of the present work was to study the antidiabetic effect of ethanolic extract of Murraya koenigii stem bark (EEMK) in alloxan-induced diabetic rats. Materials and Methods: Male Wistar albino rats weighing between 150-250 g were used for this study. The rats were divided into five groups (n=6). Group, I served as the diabetic control, group II served as diabetic control, groups III, IV served as test groups, and group V served as a standard group. The diabetes was induced by a single dose of alloxan (140 mg/kg, i.p.) in all the groups except normal control group. Then the rats of respective groups were treated with normal saline, EEMK (125 mg/kg and 250 mg/kg) and metformin (50 mg/kg) for 11 days. Blood glucose estimation was performed on 0, 1, and 11 days. At the end of this study period, animals were sacrificed for studying biochemical parameters. Results: Alloxan-induced diabetic rats showed marked hyperglycemia at the end of the study period. Body weight and liver glycogen levels were...
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Posted by admin on Jun 12, 2019 in |
A study on nutritional and microbial analysis of Kunapajala with different storage interval was conducted in the Department of Soil Science & Agricultural Chemistry and Department of Plant Pathology, UBKV, Coochbehar – 736165, West Bengal during March 2019. The motive of this work was to estimate the physicochemical properties, macro, and micronutrient content, and various microbial load of Kunapajala with a different storage time interval. Kunapajala was rich in N, P, K, Ca, Mg, S, Fe, Zn, Cu & Mn and it had a significant beneficial microbial load of Fungi, Actinomycetes, Pseudomonas, solubilising phosphorus bacteria (PSB), Azotobacter, Azospirillum, Rhizobium and Trichoderma. Nutrient content and microbial population change significantly with time in Kunapajala. So, continuous foliar and soil application of Kunapajala from the beginning and up to 40 days after preparation was beneficial to get maximum utilization. It is recommended that Kunapajala can be used as an alternative against chemical fertilizers and pesticides to develop organic...
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Posted by admin on Jun 2, 2018 in |
Unprecedented growth in popularity of complementary medicines raised concerns about their quality and safety. So, there is a need to develop methods for their sensitive, specific and accurate analysis. Authenticity and similarity of medicinal nutrients and strict procedures of material handling are significant features to maintain the quality of herbal preparations. Genome-based methods to authenticate these plants revolutionized the authentication process. Developing DNA molecular markers by sequencing a standard zone of the DNA is the best technique to identify the adulterants as well as to authenticate the required species of medicinal plants. Application of molecular biological technique serves as one of the very consistent systems for authentication of natural herbal materials. The progress of authentic analytical methods is a major challenge to scientists as natural products are optimized as drug-like molecules. Current work is based on the use of PCR technique for authentication of Glycyrrhiza glabra L. standard crude root and in polyherbal formulations i.e., Hamdard’s Joshanda, Marhaba’s Joshanda, GNC Herbal supplement and Joshaba Sadar (Chest Tea) available in...
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Posted by admin on Jun 2, 2018 in |
Objective: To study detailed pharmacognostic characters of the stem of Nyctanthes arbor-tristis (Oleaceae), along with their physicochemical parameters, fluorescence analysis, and phytochemical screening. Methods: The pharmacognostic characters were determined in terms of macroscopy, microscopy, powder microscopy, physicochemical analysis, fluorescence analysis and preliminary phytochemical investigation of the plant stem. Results: The microscopic study shows the general characteristic of the stem. Physico-chemical investigation shows the total ash, acid insoluble ash, water-soluble ash were 8.69 ± 0.17% w/w, 0.21 ± 0.11% w/w, and 3.92 ± 0.05% w/w respectively. Phytochemical analysis revealed the presence of various phytochemical groups like alkaloids, glycosides, steroids, phenolic, tannins constituents. Conclusion: It can be concluded that the established pharmacognostic profile of Nyctanthes arbor-tristis stem will help develop pharmacopoeial standards for correct identification and quality...
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Posted by admin on Jun 2, 2018 in |
The free radical scavenging activity of ethanolic root extract of Aporosa lindleyana (EREAL) was evaluated in-vitro with the spectrophotometric method based on the inhibition of hydroxyl radical, the reduction of stable DPPH free radical, inhibition of superoxide anion radical, total antioxidant activity and reducing power. Preliminary phytochemical screening showed the presence of phenolic compounds and flavonoids. EREAL showed significant activities in all free radical scavenging assays compared to standard antioxidants such as ascorbic acid, butylated hydroxyl toluene and vitamin E. In DPPH scavenging assay the IC50 value of EREAL was 215.51 µg/mL, while vitamin E had 299.11 µg/mL. Furthermore, EREAL showed good free radical scavenging activity on reducing power, superoxide anion radical activity, total antioxidant activity, hydroxyl radical activity and had good reducing...
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