Posted by admin on Jun 30, 2020 in |
Urolithiasis is a complex process that occurs from the various physiochemical event, including super-saturation aggregation, nucleation, growth, nucleation within the kidney. Data from different types of studies revealed that phytomedicines useful as an alternative remedy for the management of Urolithiasis. Terminalia chebula has been reported to possess antiurolithiatic property. The fruits were extracted in aqueous by maceration. In-vitro study was conducted to study the anti-urolithiatic effect of fruits of a macerated aqueous extract with standard drug Cystone. The titrimetric method was performed to evaluate the dissolution of stone crystal. Aqueous extract of fruits of Terminalia chebula proved a significant effect compared with standard drug Cystone. Aqueous extract of fruits of Terminalia chebula dissolves 48% crystal while Cystone dissolved 62% calcium oxalate crystal in an in-vitro...
Read More
Posted by admin on Jun 30, 2020 in |
Introduction: Picrorhiza kurroa is a well-known plant used in Ayurvedic medicines belonging to the family, Scrophul-ariaceae. This herb has been traditionally used in treating liver disorders, upper respiratory tract disorders, reduce fever, scorpion stings, and treat dyspepsia and chronic diarrhea. Experiment: The macroscopy, microscopy, powder microscopy, physiochemical screening was done on Picrorhiza kurroa roots. TLC, HPTLC. Results: The macroscopy, microscopy, and powder microscopy study reveals the identification of P. kurroa root. The phytochemical studies showed the presence of secondary active constituents such as phenols, glycosides, etc., TLC and HPTLC analysis showed that the chloroform fraction of P. kurroa has a higher number of peaks and spots compared to total...
Read More
Posted by admin on Jun 30, 2019 in |
Two indigenous plants Clerodendrum colebrookianum walp and Centella asiatica Linn. were selected to determine its cardioprotective activity on male Wister albino rats. Empirical research was designed to evaluate the cardioprotective activity of the leaves of both with special reference to its putative protective role. Aqueous methanolic extracts of both the plants were prepared by continuous hot percolation method. Male albino rats of Wistar strain (250-300 g) were used for the study. Animals were divided into 10 groups of six animals each. Both pretreatment and post-treatment study was done for 16 days at two different doses of 300 mg/kg body weight and 700 mg/kg body weight, respectively. Carbon tetrachloride was used as a cardiotoxic agent. The in-vivo biological studies on serum and tissues of male Wister rats at the doses of 300 mg and 700 mg/kg body weight respectively was carried out taking silymarin as standard. The methanolic extract of both improved the cholesterol level along with significant improvement of SGPT (Serum glutamate pyruvate transaminase), SGOT (Serum glutamate oxaloacetate transaminase),...
Read More
Posted by admin on Jun 30, 2019 in |
The present study was carried out to evaluate the wound healing potential of ethanolic flowers extract of Bauhinia acuminata in two different types of wound models in Albino rat viz., incision and excision, and compare the effects with standard drug povidine iodine ointment. The ethanolic extract at a dose of (250 mg/kg) possesses a significant increase in wound contraction and formation of scar in an excision wound model. The extract showed a significant increase in the breaking strength of resutured incision wound as compared to the control group (p<0.05). The result of the present study indicates that ethanolic flowers extract of B. acuminata posses significant wound healing in excision and incision wound model. The presence of phytoconstituents like flavonoids, saponins, phenols either individually or combined may exhibit the synergistic effect towards the healing of...
Read More
Posted by admin on Jun 30, 2019 in |
Environmental pollutants apart from other factors like habitat loss and interventions of invasive species, is regarded as a likely cause towards a worldwide decline in amphibian population. The present study attempts to elucidate the toxicity of commercially formulated malathion (MAT) by investigating biochemical aspects in Dattaphrynus melanostictus tadpoles. Three sublethal concentrations of MAT (1.0, 1.8, and 2.5 mg/l) were considered to which the tadpoles (Gosner stage 27) were exposed for five days. The outcome of the present investigation revealed a significant decline (P<0.05) in activities of catalase, superoxide dismutase, glutathione peroxidase while suggesting a significant elevation in lipid peroxidation. The inhibition acetylcholinesterase activity confirmed MAT as anticholinesterase product. The overall outcome of the present investigation suggests the toxic potentials of MAT; which could have possibly resulted in compromised antioxidant status and neurobiochemical makeup of the exposed tadpoles. Thus, based on the results obtained, it could be ascertained that the commercial grade MAT may pose a potential threat to the tadpoles of D. melanostictus under the selected sublethal concentrations. The...
Read More