Posted by admin on May 31, 2024 in |
Herbal medicine, also known as Herbalism or Botanical medicine, harnesses the therapeutic properties of plants in various forms to prevent, treat, or promote health and well-being. Plants contain a diverse array of chemical compounds that interact with the body, leading to their widespread use in traditional and modern medicine worldwide. Over the past few decades, there has been a significant rise in the global and national markets for herbal drugs. Utilized since ancient times, medicinal plants are fundamental to traditional healing systems such as Ayurveda, Unani, as well as folk and native medicine. Helicteres isora L. (Sterculiaceae family) is renowned for its traditional uses and widespread distribution. Research indicates that extracts derived from its leaves, bark, fruits, and roots possess a range of beneficial properties, including antioxidant, anti-dysenteric, anti-diabetic, and antimicrobial activities. Notably, the fruit extract of H. isora demonstrates promising free radical scavenging abilities. This review aims to provide a scientific basis for the indigenous therapeutic claims associated with bioactive fractions extracted from H....
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Posted by admin on May 31, 2024 in |
In the present study, an attempt was made to investigate Pharmacognostical studies on the stem bark of Annona glabra (Annonaceae). The plant was identified and authenticated by Dr. V. Rama Rao, Research officer (Botany), Central Ayurveda Research Institute, Bengaluru. The macroscopical studies have been carried out on the stem bark. The Characters of transverse section of stem bark shows periderm, consisting of 3-4 layers of cork, 2-3 layers of phellogen and 6-7 layers of Phelloderm. The cortex region shows the presence of parenchymatous cells. Group of fibres in patches in the outer and inner cortex. The secondary cortex consists of moderately thick-walled, parenchymatous cells. Medullary rays were present, these are bi, tri or multiseriates in the region of the inner secondary phloem. Starch grains are present. The longitudinal section shows multiseriate ray initials and single, long, septate fusiform initials, ends are arranged at different levels fusiform initials or non-stratified cambium. Starch grains are also present in the parenchyma cells. Powder shows reddish brown in colour, fragments of parenchymatous cells...
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Posted by admin on May 31, 2024 in |
In this study, Pleurotus ostreatus polysaccharide (POP) is isolated, refined, structurally analysed, and its anticancer properties are investigated. Polysaccharide yield was 6.27%, purified via DEAE-52 and Sephadex S-300 chromatography, with a molecular weight of 154649.8 Da. Structural analysis through FT-IR, HPLC, GC-MS, and NMR revealed POP as a homopolysaccharide composed of D-glucose units, featuring (1→6)-α-D-Glcp backbone with O-6 branches and T-α-D-Glcp terminations. These findings contribute to understanding the biological potential of POP. POP’s antitumor activity study showed that, with an IC50 of 121.801 µg/mL, it was highly cytotoxic to EAC cell types, supported by LDH release analysis. POP inhibited cell migration, invasion, and colony formation, indicating its potential as an anti-cancer agent. Analysis using flow cytometry showed that POP induced apoptosis, which raised the expression of Bax and Caspase-9 while decreasing the expression of Bcl-2. DNA fragmentation assay showed characteristic laddering pattern, confirming apoptosis-mediated DNA degradation. Furthermore, alterations in the expression of the proteins p53, Cyclin D, and Cdk4 were linked with POP-induced cell cycle arrest in the G0/G1...
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Posted by admin on May 31, 2024 in |
The Cucurbitaceae family has been utilized as a medicinal option in human medicine from ancient times. The bottle gourd (Lagenaria siceraria) is popularly known as lauki, ghia or dudhi in India. This is grown worldwide in the tropical climates of Africa, Asia, the Americas, and Europe. There are over 800 species and 130 genera in this family. Because of their potential for therapeutic use, researchers have looked into a variety of plants in this family, including Lagenaria siceraria. L. siceraria has been linked to several health benefits for humans, including antioxidant, immunosuppressive, hepatoprotective, hypolipidemic, diuretic, laxative, analgesic, antihypertensive, cardioprotective, central nervous system stimulant, anthelmintic, and free radical scavenging. This plant’s fruit is frequently consumed as a low-calorie vegetable. The biological chemicals found in the species are diverse and include terpenoids, flavonoids, sterols, and saponins. The edible portions of this plant also contain proteins, terpenoids, flavonoids, vitamins, choline, and other phytochemicals. In addition to 17 distinct amino acids, the seeds of L. siceraria have been discovered to contain several minerals. Per 100 g of...
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Posted by admin on May 31, 2024 in |
The genus Ficus, including Ficus racemosa, represents a significant group of trees renowned for their medicinal properties across various traditional healing systems. Widely known as Goolar in India, this medium-sized tree from the Moraceae family is abundant throughout the country, distributed from Himalayan ranges to south India. The different parts of plant Ficus racemosa like root, bark, stem, fruit, latex and leaves are rich in numerous phytochemical compounds such as alkaloids, tannins, saponins, β-sitosterol, and lupeol, contributing to its diverse therapeutic capabilities. Referenced in ancient Ayurvedic, Siddha, Unani, and Homeopathic traditions, this plant exhibits a wide array of medicinal activities, including hypoglycemic, antioxidant, hepatoprotective, antiulcer, gastroprotective, antitussive, anthelmentics, antipyretics, wound healing, anticholinesterase and anticarcinogenic properties, among others. This comprehensive review delves into taxonomy, synonyms, vernacular names, ethnobotanical uses, phytochemicals, and pharmacological evaluations of various extracts from its leaves, fruits, stems, bark, and latex, employing solvents such as ethanol, methanol, acetone, petroleum ether, ethyl acetate, and...
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