Posted by admin on Jun 30, 2023 in |
Aim: This study reviews the anti-diabetic property of Calotropis procera leaf extract. Calotropis procera used for different pharmacological activities. Calotropis procera has a number of phytoconstituents which are: Cardenolides, Terpenes, Flavonoids, Enzyme and other more components which are used to treat a number of diseases. They have some pharmacological activities like: cytotoxic activity, anti-diabetic, antioxidant, analgesics, anti-inflammatory, anti-arthritic, anthelmintic, antimicrobial, wound healing, hepato-protective, immune response, myocardial infarction and so on. Calotropis procera plant which is used to treat diabetes, it inhibit the α-amylase and α- glycosidase enzyme that are responsible for increasing the blood glucose level. Methanolic Extraction and Aqueous extraction of the Calotropis procera leaf is used as a drug. We also can use these extractions in novel technologies to treat the disease. It was studied by in-vitro testing of the extraction, which inhibits the particular enzyme by the non-competitive enzyme inhibition mechanism. Calotropis procera having a major effect of anti-diabetic inhibits these enzymes. Calotropis procera is the major source of anti-diabetic agents acting on the carbohydrate enzymes...
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Posted by admin on Jun 30, 2023 in |
Introduction: The Zingiber zerumbet (L.) Roscoe ex Smith plant, popularly known as shampoo ginger, is a member of the Zingiberaceae family also popular as wild ginger, pine cone ginger, Martinique ginger, and pinecone lily. The species is indigenous to Malaysia, Indonesia, and tropical Indo-Malesian India. It is commonly grown in the Asian tropics, specifically in China (Guangdong, Guangxi, Yunnan), Taiwan, Cambodia, India, Laos, Indonesia, Malaysia, Myanmar, Sri Lanka, Thailand, and Vietnam. The distribution of it is currently pantropical. Zerumbet Ginger is a subterranean tuberous rhizome that is pale yellow on the interior and a tall, erect, herbaceous plant with pseudostems that grows in bunches up to 0.6-2 m tall. The rhizome powder is used in many places to treat severe pain, toothache, asthma, cough, worms, leprosy, and other stomach problems. Method: Utilizing databases such as Research Gate, Science Direct, Web of Science, and Google Scholar, Pub Med, Scopus, and online books along with some botanical websites a literature review was completed. Results: The result or the review study of...
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Posted by admin on Jun 30, 2022 in |
Phytopharmacology is always a vital way for drug discovery. Antibiotic resistance is rising as a challenging threat day by day. Diarrhea and pain are always common problems. The present study was designed to evaluate the Analgesic, Antidiarrhoeal, and Antibacterial activities of ethanol extracts of leaf of Limnophila polystachya Benth by different methods. The analgesic activity of the samples was studied using the acetic acid-induced writhing model in mice. The Thomas method observed castor oil-induced antidiarrheal activity, and antimicrobial activity was monitored by the disc diffusion method. At a higher dose (500 mg/kg), Limnophila polystachya Benth inhibited 65.79 % and 63.16 % writhing of stem and leaf acetone extracts, respectively, compared to standard drug Diclofenac sodium inhibited 78.07 %writhing. Further study is needed to find possible active ingredients and mechanisms of action as well. At a higher dose (500 mg/kg) of the acetone stem and leaf extracts, significant inhibition of 50.58 and 52.87 % of characteristic diarrhoeal feces was observed, respectively, and at a lower dose (250 mg/kg) of both...
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Posted by admin on Jun 30, 2022 in |
Cupressus macrocarpa (C. macrocarpa) is an evergreen tree with medicinal uses. The essential oil of C. macrocarpa possesses a powerful antimicrobial and antifungal effect against several bacteria and fungi. We aimed of this study to evaluate the antibacterial activity of C. macrocarpa. Fresh leaves of C. macrocarpa were collected and dried in the shade at room temperature. The essential oil was obtained using hydrodistillation, and yield was recorded. The antibacterial activity of the essential oil against Staphylococcus aureus, Pseudomonas aeruginosa and Proteus vulgaris was examined, and minimal inhibitory concentration (MIC) was determined using a microdilution assay. As a result, the yield of essential oil from dried and fresh leaves was 0.39% and 0.4%, respectively. The MIC was 0.01 (v/v) for both Staphylococcus aureus and Proteus vulgaris, where the essential oil exhibited lower activity against Pseudomonas aeruginosa with a MIC of 0.04 (v/v). These results show the importance of using Cupressus macrocarpa essential oil to treat infection of several known resistant...
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Posted by admin on Jun 30, 2022 in |
Carissa carandas Linn. is an evergreen plant of the Apocynaceae family. It is native to India and also found in Bangladesh, Sri Lanka, Indonesia, Malaysia, Pakistan, and Myanmar. Almost every part of these plants has been investigated for various pharmacological activities. Among all parts, leaves are less investigated. The present study explores the hepatoprotective activity of 60 % ethanolic extract of leaves of Carissa carandas Linn. Extraction of fresh mature leaves by the process of maceration using Petroleum ether gave 0.84 gm crude extract and a yield of 1.68 %. Extraction by using 60 % Ethanol gave 6.9 gm and a yield of 13.8 %. This crude extract was investigated for the evaluation of a hepatoprotective activity. The carbon tetrachloride (CCl4) induced method was used to study hepatoprotective activity. The extract showed significant dose-dependent hepatoprotective activity when compared with negative control group as the release of enzymes and bilirubin decreased with increasing dose of...
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