Posted by admin on Jul 13, 2015 in |
In Ethiopian folk medicine, aqueous decoction of the leaves of Salvia schimperi is used for treatments of various ailments including diarrhea, however, to date, there appear to have been no reports on the phytochemistry, the antidiarrhoeal and the antimicrobial activity of the plant. In this study, the hydroalcoholic extract of the leaves of S. schimperi was evaluated for its antidiarrheal and antibacterial activities against castor oil induced diarrhea in mice and six clinically isolated enteric bacterial pathogens using standard agar diffusion methods, respectively. The minimum inhibitory concentrations (MIC) of the extracts were also determined using the microdilution method. The extract exerted significant and dose-related antidiarrhoeal activity when compared to the control and the standard drug, loperamide. The extract displayed highest antidiarrhoeal activity at a dose of 400 mg/kg which is comparable with that of the standard drug loperamide. The extract also showed moderate antibacterial effects against most of the test microorganisms except S. typhimurium. Phytochemical analysis of the extract revealed the presence of polyphenolic compounds such as flavonoids and...
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Posted by admin on Jul 13, 2015 in |
Rapid industrialization and modernization have introduced substantial amounts of toxic heavy metals into the aquatic and terrestrial environment which possess a severe threat to flora and fauna. In recent years, considerable research work has been done and is currently underway on some natural biopolymers and their modifications to remove different kinds of heavy metal ions. Chitosan and cellulose, both naturally occurring polysaccharides are the most effective adsorbents for the removal of heavy metal ions from wastewater. This review is aimed to provide relevant and recent information on the application of chitosan, cellulose and their respective derivatives for the removal of toxic heavy metal...
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Posted by admin on Jul 13, 2015 in |
The genus Ruellia L. is sometimes called Dipteracanthus, it comprises about 150 species native to tropical and temperate North and South America. In this review, the literature data on phytochemical and biological investigations of the genus Ruellia are compiled. The well-recognized groups of secondary metabolites were flavonoids, lignans, coumarins, alkaloids, triterpenes, sterols, phenolic glycosides, phenylethanoids, megastigmane glycosides, benzoxazinoid glucosides, and others. The extract of this genus as well as pure compounds isolated from it have been demonstrated to possess multiple pharmacological activities such as wound healing, cardio-vascular, anti-hyperglycemic, antioxidant, antimicrobial, antibacterial, anticancer, antinociceptive, anti-inflammatory, cytotoxic and gastro-protective activities, purgative and angiotensin-converting enzyme-inhibitory effects, estrogenic and cholinergic properties and anti-fertility...
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Posted by admin on Jun 1, 2014 in |
The present study is part of the continuing programme related to the antihelminthic activity and phytochemical screening of Andrographis paniculata Nees. (Kalmegh) and their enhanced potential on helminths. The antihelminthic activity of the aqueous extract of Andrographis paniculata Nees. leaves against the adult Indian earthworms Pheretima posthuma due to its anatomical and physiological resemblance with the intestinal roundworm parasites of human beings. Several plant species are administered orally to control the various diseases in our country. Some of these plants have been pharmacologically provided to be of some value and maybe a popular remedy for the treatment of various ailments. The growth of knowledge to cure disease continues at an accelerating pace and number of new plant-derived drugs increase likewise. Herbal medicine is currently experiencing a revival in Western society along with other complementary therapies such as traditional Chinese Medicines, Osteopathy and Homeopathy. In this context, the present study is the first milestone with particular emphasis on the application of Andrographis paniculata Nees. (Kalmegh) the medicinal plant, their antihelminthic...
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Posted by admin on Jun 1, 2014 in |
Kidney stone is a painful disease which is a major problem in all regions of Pakistan as this country is located in the so-called stone belt. Drastic changes in dietary habits including the use of soft drinks are increasing the incidence of kidney stone disease. To investigate this phenomenon, calcium oxalate monohydrate crystals were induced in artificial urine by mixing calcium chloride and sodium oxalate in-vitro and different types of soft drinks were analyzed for activity against calcium oxalate monohydrate type’s kidney stone. Most of them showed effects on calcium oxalate monohydrate to calcium oxalate dihydrate crystals under DIC microscopy. This study showed that slices had the most promising effect on calcium oxalate monohydrate crystals than Mirinda and Mountain dew. 7up and Pepsi did not show a change in morphology of the crystals of calcium oxalate...
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