Posted by admin on May 17, 2016 in |
The study is aimed at the development of physicochemical parameters and to investigate the active principle present in Chlorophytum borvilianum and Sapindus mukorrossai. The present work embodies the investigations carried out to establish methods for quality control of drugs as per WHO guidelines: complete botanical evaluation which comprises of macroscopy, quantitative microscopy, powder microscopy, physicochemical parameters like loss on drying, extractive values, saponification value, total ash values, acid insoluble ash value, water-soluble ash value, pH value, loss on drying, bulk density and fluorescence analysis of powdered drug to investigate the phytochemicals present in the extracts in the preliminary...
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Posted by admin on May 17, 2016 in |
The aim of the present study, synthesis of new compounds of 4-methyl coumarin derivatives, from starting material (7-dihydroxy-4-methyl coumarin). A variety of chalcones derivative have been synthesized, and the proposed structures were confirmed by physical properties like UV –Visible, FT-IR and ¹ H NMR, Chem Bio Draw was used to evaluated the geometry optimization and total energies as well as dipole moment for all prepared...
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Posted by admin on May 17, 2016 in |
Gynura procumbens (GP) commonly known as longevity spinach is one of those precious medicinal herbs of Asteraceae that are still included in a un-utilized herb in spite of the variety of useful pharmacological properties it possesses. It is mainly popular in South-East Asian countries for its traditional medicinal properties. It is usually used as a traditional medicine for the treatment of inflammation, herpes simplex virus, rashes, fever, rheumatism, kidney diseases, migraines, diabetes mellitus, cancer, and hypertension. This article provides the collective information about the phytochemical constituents isolated from leaves of this plant used in a modern scenario for the treatment of various ailments like kaempferol-3-O-rutinoside, astragalin, rutin, kaempferol, sterol glycosides, flavonoids, saponins, tannins, and terpenoids, etc. Here, we have reviewed all the reported pharmacological properties such as anti-inflammatory, anticancer, anti-diabetic, anti-herpes simplex virus, anti-ulcerogenic, vasorelaxant, toxicity, and some other...
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Posted by admin on Apr 29, 2015 in |
Butea monosperma var. lutea, a native of India, is commonly known as “Palash” and popularly known as “Flame of Forest.” Traditionally it has been found that flowers have antimicrobial, wound healing, antifungal, antidiarrhoeal, hypoglycemic, hepatoprotective, antioxidant, anthelmintic, anti-convulsive, antistress, antidiabetic, anti-inflammatory activity. In the present study, crude hydroalcoholic flower extract was examined for anticancer activity. To determine in-vitro anticancer activity, different concentrations of crude extract were tested on MCF-7 breast cancer cell line by 3-(4,5-dimethyl thiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The extract showed significant antiproliferative activity and a dose-dependent effect. Minimum inhibition 16.8% was shown by extract at concentration 62.5 µg/ml and maximum inhibition (46.89%) observed at 500 µg/ml. The flower extract showed activity in the potential range for further investigation of cancer cells....
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Posted by admin on Apr 29, 2015 in |
Phytochemicals are the best remedies to all kind of diseases and disorders throughout the world. There are a lot of plants, and its sources are playing a role as a heart, liver and kidney savers. In our present investigation, the famous fruit tree Annona squamosa (Annonaceae) leaves extract used for the hepatoprotective activity. The phytochemicals present in the aqueous leaves extracts were analyzed using preliminary biochemical analysis, and functional groups are characterized using Fourier Transform Infrared Spectrophotometer (FT-IR). The animals were divided into six groups, in that apart from the first group (normal control), five groups are induced with paracetamol (acetaminophen) with standard drug and two plant drug extracted by aqueous one is induced control. The increasing of enzymes and bilirubin, triglycerides and cholesterol and decreasing protein shows the liver damage. These levels are changed into normal range indicates efficiency of our plant drug. The histopathalogical results are also confirmed our hepatoprotective capability is...
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