Posted by admin on May 17, 2016 in |
The hypolipidemic activity of Aloe vera (Family: Liliaceae) extract has been studied in two models of hyperlipidemia in rats. In an acute model, hyperlipidemia was induced by injecting a single dose of triton WR-1339 (400mg/kg, b.w.) intraperitoneally in rats. Feeding with Aloe vera extract at the dose of 500 mg/ kg, b.w. exerted a significant lipid-lowering effect as assessed by the reversal of plasma levels of total cholesterol (TC), phospholipids (PL), triglyceride (TG) and reactivation of post-heparin lipolytic activity (PHLA). In the chronic model, hyperlipidemia was induced by feeding with cholesterol-rich- HFD in rats. The treatment with seeds extracts of Aloe vera (500 mg/ kg b.w) simultaneously for 15 days also caused lowering of lipid levels in plasma and liver following reactivation of plasma post-heparin lipolytic activity and hepatic lipoprotein lipase activity in animals. The hypolipidemic activity of Aloe vera was compared with a standard drug guggulipid (200 mg/ kg, b.w.) in both...
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Posted by admin on May 17, 2016 in |
The present investigation has been carried out to determine the antioxidant activity of the ethanolic extracts obtained from plant seeds belonging to family Leguminosae i.e., Lens culinaris, Vigna unguiculata, Dolichos biflorus and Phalaseous. Phenolic compounds present in the extracts showed the antioxidant and antiradical properties when investigated using a ferrous ion chelating ability and reducing power assay. The results indicated that ethanolic extracts of all four plant seeds resembled in the activities above. Phenolic constituents contained in plant mentioned above seeds may have a future role as ingredients in the development of functional...
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Posted by admin on May 17, 2016 in |
The study is aimed at the development of physicochemical parameters and to investigate the active principle present in Chlorophytum borvilianum and Sapindus mukorrossai. The present work embodies the investigations carried out to establish methods for quality control of drugs as per WHO guidelines: complete botanical evaluation which comprises of macroscopy, quantitative microscopy, powder microscopy, physicochemical parameters like loss on drying, extractive values, saponification value, total ash values, acid insoluble ash value, water-soluble ash value, pH value, loss on drying, bulk density and fluorescence analysis of powdered drug to investigate the phytochemicals present in the extracts in the preliminary...
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Posted by admin on May 17, 2016 in |
The aim of the present study, synthesis of new compounds of 4-methyl coumarin derivatives, from starting material (7-dihydroxy-4-methyl coumarin). A variety of chalcones derivative have been synthesized, and the proposed structures were confirmed by physical properties like UV –Visible, FT-IR and ¹ H NMR, Chem Bio Draw was used to evaluated the geometry optimization and total energies as well as dipole moment for all prepared...
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Posted by admin on May 17, 2016 in |
Gynura procumbens (GP) commonly known as longevity spinach is one of those precious medicinal herbs of Asteraceae that are still included in a un-utilized herb in spite of the variety of useful pharmacological properties it possesses. It is mainly popular in South-East Asian countries for its traditional medicinal properties. It is usually used as a traditional medicine for the treatment of inflammation, herpes simplex virus, rashes, fever, rheumatism, kidney diseases, migraines, diabetes mellitus, cancer, and hypertension. This article provides the collective information about the phytochemical constituents isolated from leaves of this plant used in a modern scenario for the treatment of various ailments like kaempferol-3-O-rutinoside, astragalin, rutin, kaempferol, sterol glycosides, flavonoids, saponins, tannins, and terpenoids, etc. Here, we have reviewed all the reported pharmacological properties such as anti-inflammatory, anticancer, anti-diabetic, anti-herpes simplex virus, anti-ulcerogenic, vasorelaxant, toxicity, and some other...
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