Posted by admin on Oct 31, 2018 in |
Objective: To study detailed pharmacognostic profile and preliminary phytochemical investigation of the leaves of Indigofera tinctoria Linn. commonly known as ‘indigo’ belongs to the family Fabaceae. It is distributed through the hotter parts of India. Medicinal uses include the juice of the leaves as a prophylactic against hydrophobia, and as a decoction for blennorrhagia; plant extract as the treatment for epilepsy, nervous disorders, bronchitis, and as an ointment for sores, old ulcers, and hemorrhoids; and roots for hepatitis, scorpion bites, and urinary complaint. Methods: Leaf of I. tinctoria Linn. was studied by macroscopical, microscopical, quantitative microscopy, physicochemical, phytochemical analysis of leaf powder of the plant and other methods for standardization recommended by WHO. Results: Macroscopically the leaves with 9-13 leaflets and broken pieces of rachis, opposite, oblanceolate with very short mucronate tip, pale greenish black, mucronate apex, cuneate base, smooth texture, characteristic odor and taste. Leaflets 1-2.5 cm long and 0.3-1.2 cm wide. Microscopically, the leaflet appears wavy in T.S. view; prominent adaxial and abaxial thickening, the vascular bundle...
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Posted by admin on Oct 31, 2018 in |
Azadirachta indica (A. indica) belongs to the family Meliaceae. Various parts of the plant, including root, are used as a drug for various ailments, including malaria. The purpose of this study was to determine the chemical composition of essential oil (EO) of the root of A. indica collected from North Central Nigeria. The root essential oil of Azadirachta indica was obtained by using hydrodistillation method. Gas Chromatography, coupled to mass spectrometry, was used to analyze and determine the chemical composition of the essential oil. Mass spectra were searched against Mass Spectrometry databases, and twenty-eight components were identified. The main constituents citronellic acid (29.60%), 1-bromotriacontane (8.59%), totara-8,11,13-triene-7.beta.,13-diol (8.26%) and 4,8,12,15,15-pentamethyl-bicyclo[9.3.1]pentadeca-3,7-dien-12-ol...
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Posted by admin on Oct 31, 2018 in |
Aim of Study: Compare the macroscopic and microscopic study of Acacia arabica and Prosopis juliflora. Material and Methods: The ethanolic extract of on Acacia arabica and Prosopis juliflora were using physio-chemical parameters and preliminary phytochemical investigation. Results and Discussion: In this study. I have done the comparative pharmacognostic study on Acacia arabia and Prosopis juliflora and conclude that the ethanolic extract of Acacia arabica plays a more significant role and has more significant value than the extract of Prosopis juliflora. Conclusion: The present study was aimed at the pharmacognostical study. Plants Acacia arabica and Prosopis juliflora were studies for pharmacognostical characteristic, namely, morphology, microscopy, which can be of utilized in identification and authentication of...
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Posted by admin on Oct 31, 2018 in |
The optimization of aqueous and non-aqueous solubility of a drug or a drug-like molecule can be examined via the Aspen Plus simulation platform. Paracetamol (solute) will be taken as a case study. The following solvents were used in our dry (virtual) lab experiment: water, paracetamol (PARACTML), used as a solid solute, Di-Ethylene-Glycol (DEG), 1,2-Propanediol (PROPGLYC), and Poly-Ethylene-Glycol (PEG). A simplified flow sheet made of a single mixing tank where it has three feed streams, representing the solute, the water, and the set of organic solvents and one product stream where paracetamol is solubilized (liquid solution). Three different objective functions were used: Minimization of both the molar Gibbs free energy of mixing, ∆Gmix, and the molar Gibbs free energy of the mixture, Gmix, and maximization of the mass solubility of paracetamol in solution, expressed in g/L. The NRTL property method was used to analyze the solution properties. Using the molar Gibbs free energy, Gmix, as a criterion of solution thermodynamic stability, it was found that a binary non-aqueous mixture made...
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Posted by admin on Oct 31, 2018 in |
Antigonon leptopus Hook & Arn (family Polygonaceae), also called: Chain of love, Queen’s Wreath and Mexican creeper is a fast-growing vine with stems reaching up to 20 feet long. It has heart-shaped, green leaves climbing by tendrils which wrap around many types of supports. It is native to Mexico and commonly found in tropical Asia, Africa, the Caribbean, and the Americas. It possesses anticoagulant activity, analgesic, anti-thrombin, anti-inflammatory, anti-diabetic, and anti-depressant activities. Aerial parts of the vine have been used as hepatoprotective and for spleen disorders. The vine was hardly growing and greatly affected by the relatively high temperature, as well as a shortage of water throughout the year in “El-Zohreya” Park, Cairo; thus to increase the plant propagation a tissue culture study was conducted. The formation of callus tissue from the leaf explants revealed promising results. Detection of the flavonoidal content by HPLC analysis was also performed on the different callus cultures, supplemented with different concentrations of the growth hormone regulator naphthalene acetic acid...
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