Posted by admin on Nov 1, 2014 in |
The inhibitory effects of ethyl acetate, aqueous and ethanolic extracts of Talinum triangulare were well observed in the brain homogenate of Swiss albino rats against sodium nitroprusside induced-peroxidation by thiobarbituric acid reactive species (TBARS) in-vitro. All the extracts showed significant inhibitory abilities against sodium-nitroprusside (SNP) induced lipid peroxidation in the brain homogenate when incubated with 60mM sodium nitroprusside. In the current work, aqueous extract of Talinum triangulare seems to possess higher antioxidant contents with the fact that it shows the highest inhibition potential against SNP-induced peroxidation in the brain tissue homogenate from the results, thereby characterize the ability to protect the brain cell and as well able to prevent nitrosative stress induction at considerable measure in the...
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Posted by admin on Nov 1, 2014 in |
In folk medicine, Aloe camperi, Aloe percrassa (Aloeceae), and Senna singueana L. (Fabaceae) are used in the management of infectious and inflammation-related disorders. The objective of this work was to evaluate the in-vitro hyaluronidase inhibition activities of extracts from these three medicinal plants. Various concentrations (10, 50, and 100 µg/ml) of leaf latex from the two Aloe sp and hydro alcoholic extract of S. singueana leaves were screened using hyaluronidase inhibition assay. The results showed that all the three extracts displayed concentration-dependent inhibitory activities with IC50 values of 771.78, 664.47 and 630.83 μg/ml for A. camperi, A. Percrassa and S. singueana, respectively. Indomethacin, used as a standard drug in this study, showed IC50 value of 27.95μg/ml. Hyaluronidase hydrolyzes hyaluronic acid in the extracellular matrix during tissue remodeling. Since, oligomers from hyaluronic acid degradation are associated with induction of inflammation and hyaluronidase activity up-regulation occurs in chronic inflammatory conditions, hyaluronidase inhibitors are suggested to have a beneficial role in prevention and treatment of inflammation-related disorders. Thus, the hyaluronidase enzyme inhibition...
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Posted by admin on Nov 1, 2014 in |
The current practice of medicine indebted much to the knowledge and achievements of the past. It is really surprising that far back Greco-Arab physicians were aware of the various diseases and scientifically mentioned them. Most of the knowledge is still in practice. Modern days practice relies on the fundamentals proposed by them. In the classical text of Unani Medicine, headache is described in detail. The Shaqeeqa (a migraine) is described nearly in all classical text of Unani medicine as a disease entity includes definition, etiopathology, clinical feature, and...
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Posted by admin on Nov 1, 2014 in |
The objective of this review is to update and assess the chemistry, composition, mechanism of action, pharmacokinetics, nutritional value and toxicology of garlic. The medicinal properties of garlic include immune functions, antibacterial activities, antifungal activities, antivirus activities, de-toxification, anti-oxidant agent, prevent platelet aggregation, reduction in blood pressure, lowering of cholesterol and triglyceride, prevention of arteriosclerosis, antithrombotic, anticancer effects. The scientific research shows that the wide variety of dietary and medicinal functions of garlic can be attributed to the sulfur compounds present in or produced from garlic. Chemical analysis of garlic cloves has revealed a concentration of sulfur-containing compounds (1-3%). Although garlic produces a large number of sulfide compounds from a few sulfur-containing amino acids, their functions are different from one another like allicin, diallyl, mono, di, tri, tetra, hexa and hepta sulfides, vinyldithiins and ajoenes., Allyl, propyl disulfide and other organic sulfide or sulfur compounds diallyl disulfide, allinase, alliin(S-allyl cysteine...
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Posted by admin on Nov 1, 2014 in |
Coccinia grandis Linn. Voigt, also known as Coccinia indica belongs to the family Cucurbitaceae. It is extensively used in traditional medicine for the treatment of leprosy, jaundice, asthma, bronchitis, skin eruptions, burns, tongue sores, earache, indigestion, eye infections, nausea, insect bites, and fever. Phytochemical studies reveal the presence of phenols, tannins, saponins, terpenoids, flavonoids, arabinose, xylose, mannose, galactose, glucose and rhamnose. Studies on the plant extract particularly the leaf extract shows that it possesses antihyperglycemic, xanthine oxidase inhibitory, analgesic, anti-inflammatory, and antipyretic, antioxidant, antihyperlipidemic, antimicrobial, anti-hepatotoxic and anti-insecticidal activities. Among these, the plant’s activity against diabetes has been extensively investigated. Current studies on its antioxidant activity reveal its potential in cancer therapy. The plant leaf extract also shows significant activity chemoprotective effect against cyclophosphamide, commonly used in the treatment of cancer and autoimmune diseases. A review of the various studies on the plant is provided to understand its medicinal...
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