Posted by admin on Oct 31, 2024 in |
Medicinal plants contain phytochemicals that are recognized for their wide range of therapeutic uses. Dioscorea bulbifera often referred to as the air potato or bitter yam, is a plant belonging to the Dioscoreaceae family, which includes about 600 species. It holds significant traditional medicinal importance worldwide, being used for treating various ailments. This plant is commonly found in India, Maldives, China, Japan, Indonesia, and is a staple food crop in West Africa. The plant features bulbous aerial tubers, toxic substances like the alkaloid dioscorine, and small, dioecious flowers. Dioscorea bulbifera grows in tropical and subtropical regions, preferring loamy soils and temperatures between 20°C and 30°C. It reproduces mainly asexually via bulbs. Dioscorea bulbifera is widely used in traditional Indian and Chinese medicine for conditions such as piles, dysentery, syphilis, ulcers, pain relief, and inflammation. The plant’s tubers and bulbils are noted for their cytotoxic properties, traditionally used in treating sore throats, goitre, and various other conditions. Phytochemical analyses reveal that the plant contains alkaloids, glycosides, sterols, polyphenols, flavonoids, and...
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Posted by admin on Oct 31, 2024 in |
Objective: This study aims to investigate the effects of UV light treatment and drying processes on the vitamin D2 content of oyster mushrooms (Pleurotus spp.), focusing on the difference in vitamin D concentration between mushrooms grown under UV light and those cultivated without it. Additionally, the study explores how various wavelengths of UV radiation, exposure durations, and post-treatment storage conditions influence the vitamin D2 levels. Method: Oyster mushrooms were grown under controlled conditions, with one group exposed to UV light and the other group grown without UV treatment. The mushrooms were subjected to varying wavelengths of UV radiation for different durations. Following the UV exposure, the mushrooms underwent different drying processes, including sun drying. Vitamin D2 levels were measured in both fresh and dried mushrooms, and the effect of post-treatment storage conditions was assessed. Results: Mushrooms exposed to UV light exhibited significantly higher vitamin D2 content compared to those grown without UV treatment. The concentration of vitamin D2 was influenced by the wavelength and duration of UV exposure, with...
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Posted by admin on Oct 31, 2024 in |
In biological cells, antioxidants play a crucial role in preventing cellular damage caused by oxidation of other molecules. Their primary function is to neutralize free radicals, which can have detrimental effects on living organisms. Antioxidants achieve this by reacting with free radicals, thereby terminating the chain reactions that could harm cells. This study aimed to assess the antioxidant potential of ethanolic leaves extract of Ficus virens and compared it with a standard antioxidant, such as ascorbic acid. The plant material was subjected to sequential extraction using a solvent of 70% ethanol, utilizing a Soxhlet extraction method. The phytochemicals examination ethanolic leaves extract of Ficus virens exposed the presence of alkaloids, glycosides, flavonoids, proteins, carbohydrates, Tannins and phenolic compounds. The extract was tested for total phenolic content (TPC) and antioxidant activity. Antioxidant activities were determined spectropho-tometrically using the DPPH assay, hydrogen peroxide assay, Ferric reducing antioxidant power assay, phosphomolybdate assay, nitric oxide scavenging assay. The result of ethanolic leaves extract shows the good antioxidant potency when compared with standard ascorbic...
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Posted by admin on Oct 31, 2024 in |
Antioxidants are crucial in combating oxidative stress and related diseases. This study aimed to assess the antioxidant potential of methanolic root extract of Annona glabra Linn. and ascorbic acid is used as a reference. The plant material was subjected to sequential extraction using a solvent of varying polarities, utilizing a Soxhlet extraction method. The extract was tested for phytochemicals (secondary metabolites), total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity. The phytochemicals examination of root extract of Annona glabra Linn. exposed the presence of alkaloids, glycosides, flavonoids, saponins, phenols, steroids, terpenoids. TPC, TFC of crude methanolic root extract of plant was determined using Folin-Ciocalteus reagent and Aluminum chloride colorimetric method respectively. Antioxidant activities were determined spectrophotometrically using the DPPH assay, nitric oxide scavenging assay, hydrogen peroxide scavenging assay, phosphomolybdate assay, ferric reducing antioxidant power assay. The result of methanolic root extract shows the good antioxidant...
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Posted by admin on Oct 31, 2024 in |
In the present work, fast dissolving tablets of metoprolol tartrate, were prepared using sodium starch glycolate, sodium croscarmellose and crospovidone as superdisintegrants, by the direct compression method. The tablets prepared were evaluated for various parameters including Bulk density, Tapped density, Angle of repose, Carr’s index, Hauser’s ratio, weight variation, hardness, friability, in-vitro dispersion time, drug content water absorption ratio, wetting time, in-vitro drug release. The tablet prepared by the direct compression method had a weight variation in the range of 198mg to 204mg which is below ±6.5%, Hardness of 3.7kg/cm2 to 4.3kg/cm2 , Percentage friability of 0.56% to 0.61%, in-vitro dispersion time of 18 sec to 24 sec, Wetting time of 33 sec to 51 sec and in-vitro drug release of 45.04% to 97.63% within 15 min. Fast dissolving tablets of metoprolol tartrate have enhanced dissolution and will lead to improved bioavailability and more effective therapy. The release rate of drugs from fast dissolving tablets intensifies with a rise in the concentration of super disintegrants and the metoprolol tartrate...
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