Posted by admin on Oct 31, 2023 in |
This review highlights trends in traditional medicine and medicinal plant research and has the purpose of inspiring research focusing on accelerating the integration of traditional medicines into mainstream healthcare systems. Comprehensive literature resources accessible via Google’s search engine were systematically reviewed and described. Traditional medicines in general and traditional African medicine in particular are described. The historical contribution of medicinal plant research to the start of the entire enterprise of drug discovery and development as well as the pharmaceutical industry is highlighted. The decline of traditional medicine during the 19th and 20th centuries and the revival of interest in it towards the end of the 20th century are briefed. The role of conventional new chemical entity-based drug discovery strategies and associated successes and drawbacks related to medicinal plant research plus subsequent advocates foran alternative approach based on traditional medicine inspired by reverse pharmacology by the medicinal plant research community is emphasized. Overall, this review discussed, in addition to applying the well-established and science- and technology-supported drug discovery approach, adopting...
Read More
Posted by admin on Oct 31, 2023 in |
The process of new drugs development is enforced by the success of herbal drugs in pharmaceutical market. Another approach to natural product drug discovery is to utilize the information derived. From industrial view point regarding sufficient supply of natural product derived active constituents. Musa acuminata has been used of the management of wound healing, fever, cough, bronchitis, sexually transmitted infection, allergic infection, dysentery, and non communicable diseases. This study was designed to assess its phytochemical and wound healing property on the male Wister rats. The roots of Musa acuminata is extract in Soxhlet extraction in three deferent methods (i) Chloroform extract (ii) Petroleum ether extract (iii) Ethanol extract. And for pharmacological activity five group ware created each group contain four animals which weight between 150-180gm. Group-1 is treated on normal control, Group-2 is treated on topically with hydrophilic ointment base, Group-3 is treated topically with framycetin sulphate cream 1% w/w, Brand name is soframycin, Group-4 is treated on ethanol extract, Group-5 is treat on chloroform extract and study the...
Read More
Posted by admin on Nov 30, 2022 in |
The motive behind this analysis is to grant a layout to the very familiar plant to everyone as the “Golden shower Indian laburnum “ is affiliated with the Fabaceae family which is employed as a medicinal plant that possesses pharmacological activities in the healthcare system. Pharmacologically, it is very noteworthy in curing various infirmities and performs as an anti-inflammatory, carminative, analgesic, laxative, anti-bacterial, antifungal, anti-diabetic, antioxidant, hepatoprotective, antifertility, wound healing, antiulcer, anti-tumor, antifertility, antipyretic and anti-cancer, etc. Leaves, flowers, roots, fruit, wood, pulp, pods, seeds, trunk, etc., are different parts of Cassia fistula Linn. The plant has been approved for medications for Jaundice, Gout, Fatty Liver, Liver Disorder, Bronchitis, Fever, Skin disease, Migraine, Joint pain, Cancer, Tumour and so on. The Cassia fistula Linn. has also been suggested to possess, anti-diabetic, abortifacient, hepatomegaly, rheumatic disorder, pruritus, leprosy and diuretics. It also has blood purifier activity. Cassia fistula plants are found all over India. This plant’s fruits, flowers, stem bark, and leaves contain a wide range of biologically active chemicals...
Read More
Posted by admin on Nov 30, 2021 in |
Neurodegenerative movement disorder of the central nervous system (CNS) (Parkinson’s disease (PD)) is characterized by necrosis of dopaminergic neurons within the substan tianigra pars compacta are ain the midbrain. The PD cause is still unknown and seems to be multifactorial. Oxidative stress and mitochondrial impairment have been the main consequences, which offer prominent clues regarding the disease mechanisms. The effect of free radicals and oxidative stress on the cascade of events resulting in dopamine cell degeneration in PD has been demonstrated. In-built protective mechanisms, including enzymatic and non-enzymatic antioxidants within the CNS, effectively prevent neuronal cell loss because of free radicals. However, aging is associated with a decrease in the production of these antioxidants. Thus, antioxidant therapy alone or combined with available treatment methods offers an attractive method to treat or prevent neurodegeneration in PD. We summarized the recent discoveries of potential antioxidant agents to modulate free radical-mediated oxidative stress resulting in neurotoxicity in...
Read More
Posted by admin on Nov 30, 2021 in |
Before discovering synthetic drugs, peoples were dependent completely on the herbal medicinal plants for the prevention and treatment of various diseases or ailments. This is the era where a large number of synthetic drugs have been discovered for the treatment of various diseases and better health care for people suffering from various diseases. However, herbal drugs are still the choice for treating many diseases. They are preferred over synthetic drugs as they are pharmacologically very active and have no side effects or low side effects when used for the treatment of diseases. B. serrata is one of the medicinal plants amongst many other plants used traditionally to treat various ailments or diseases. The medicinal plant has a long-range of reported pharmacological activities viz. anti-inflammatory activity, anti-arthritic activity, anti-rheumatic, analgesic activity, antimicrobial activity anti-oxidant activity, anticancer activity, antitumor activity, anti-asthmatic activity, anti-diarrhoeal activity, immunomodulatory activity, hypo-lipidaemic and hepatoprotective activity, anti-complementary activity, antifungal, anti-convulsant activity, anti-obesity, cardiotonic activity and anti-ulcer activity. The Oleo-gum-resin of the plant B. serrata is traditionally used...
Read More
