Posted by admin on Jan 1, 2014 in |
Aim of the Study: This study aimed to investigate the effect of ethanolic extract of fruits Coccinia indica Wight & Arn. (Cucurbitaceae) on urolithiasis in rats. Materials & methods: Thirty-six male rats were randomly divided into six groups (n = 6). Ethylene glycol (EG) 0.75% in drinking water were fed to all groups (Groups II-VI) except normal control (Group I) rats for 15-28th days to induce urolithiasis. Group III-VI rats were treated with ethanolic extract Coccinia indica of at doses 100, 200, 300 mg/kg, respectively, for 28 days. Positive control (Group II) rats were treated with EG alone. Group, I rats was administered drinking water and distilled water (6 μl/g) by gavage. After 15-28th days, blood samples were collected and analyzed for serum concentrations of calcium, Inorganic phosphorus, Blood urea, and creatinine. The kidneys were removed and sectioned for histopathological examination. The data were presented as mean ± standard error of the mean and analyzed using one-way analysis of variance P<0.05 was considered statistically significant. Results: In the present...
Read More
Posted by admin on Jan 1, 2014 in |
Kidney stone is one of the most prevalent disease worldwide calcium oxalate has been shown to be the main components of the majority of stones formed in the urinary system of patients with urolithiasis. The main objective is to study the inhibition effect of coleus Aromaticu benth. On the calcium oxalate crystal. The antilithiatic activity of Coleus Aromaticus was investigated on nucleation growth of calcium oxalate crystal. The effect of the extract on antilithiatic activity formed by Turbidity method at 620nm by mean of the spectrophotometer. The methanol extract of Coleus Aromaticus as shown significant activity on comparison to synthetic drug Cystone and Neeri. The maximum Percentage inhibition of calcium oxalate nucleation was found 62.48% in methanol extract. We concluded that the Methanol extract of Coleus Aromaticus Benth. act on nucleation crystal...
Read More
Posted by admin on Jan 1, 2014 in |
Emergence of new strains of Escherichia coli with the ability of resistance to a wide range of antibiotics necessitates the efforts to search alternatives for better treatments to deal with these infections. Chamomile is one of the most widely used herbs in the world. In this study, we investigated the potential therapeutic effects of chamomile chloroform extract on E. coli intraperitoneal (IP) infection of BALB/c mice. Female BALB/c with an average weight of 20 to 25 g, were divided into 8 groups. The lethal dose of the E. coli for mice has injected IP in test groups and treated with 5.25, 10.5 and 21 mg/mL of chamomile chloroform extract. The combined effect of the extract (50 µg/mg) with amikacin and amikacin alone were also examined. The highest number of survived mice at the dose of 10.5 mg/mL of extract and the highest death rate with 5.25 mg/mL of extract was observed. In the amikacin group, all infected animals were survived. The mortality rate in chamomile extract combination with amikacin...
Read More
Posted by admin on Jan 1, 2014 in |
Diabetes mellitus is characterized by elevated plasma glucose concentrations resulting from insufficient insulin. A comprehensive herbal drug therapeutic regimen offers time tested safe and effective support to conventional therapy in the management of diabetes. This is a combination with adequate dietary management, and physical activity would provide an integrated approach to the management of this deadly disease, particularly Type 2 diabetes. In this paper, an attempt has been made to give an overview of certain Indian plants with their phytoconstituents and mechanism of action which have been studied for their antidiabetic activity. The present work offers a review addressing the detailed phytochemistry of different plants contains this...
Read More
Posted by admin on Jan 1, 2014 in |
Calotropis gigantea (Asclepiadaceae) is a perennial herb with a long history of use in traditional medicines. A wide range of chemical compounds including cardiac glycosides, flavonoids, terpenoids, alkaloids, tannins, & resins has been isolated from this plant. The plant has been used for various disease condition including leprosy, ulcers, tumors and piles. Various pharmacological activities reported like analgesic activity, antipyretic activity, pregnancy interceptive activity, CNS activity, anti-inflammatory activity, procoagulant activity, anti-diarrhoeal activity, free radical scavenging activity, antimicrobial activity, anti-tumor activity, antifungal activity, antitussive activity, and antifeedant...
Read More