Posted by admin on Jan 31, 2023 in |
Sapindus emarginatus Vahl. is extensively used in Indian traditional and folklore medicines to cure various human ailments. The preliminary phytochemical screening of the leaves revealed the presence of saponins, terpenoids, tannins, acids, flavonoids, cardiac glycosides, and sugars. Saponin applications were observed due to various biological, medicinal, and pharmaceutical actions. Several other uses for Sapindus have also been reported, such as making arrows from wood and decorative objects from seeds. The presence of saponin glycosides in the plant parts produces many beneficial pharmacological actions. These Sapindus drugs contain different active constituents, which various methods of extraction and separation methods can isolate. The choice of extraction procedure depends on the nature of the plant material and the components to be isolated. Maceration extraction, Soxhlet extraction, and microwave-assisted extractions give the most effective extraction of saponins from Sapindus species. Hence, this present review article provides detailed information about the different isolation procedures of saponin...
Read More
Posted by admin on Jan 31, 2023 in |
The expansion of research on finding herbal sources for producing new effective and safe medicinal herbal remedies is an urgent pharmacy task. One of the ways to increase the amount of herbal medicinal preparations is a broad study of the pharmacological action of non-pharmacopoeial medicinal plants used in folk medicine. One of these plants is Black root officinalis (Cynoglossum officinale), which grows wild in the European part of Russia, Siberia, Central Asia, and the Caucasus, including North Ossetia, but does not form significant thickets. Today Cynoglossum officinale is used mainly in folk medicine as an anti-inflammatory, analgesic, sedative, and expectorant. When applied externally, Cynoglossum exhibits antipruritic properties and is capable of tissue regeneration. Therefore, the pharmacognostic study for further research on pharmacological effects on the human body is quite...
Read More
Posted by admin on Jan 31, 2022 in |
The solid drug dosage form, especially the tablet formulations, are made with natural polymer- microcrystalline cellulose (MCC) fibers with many other inorganic agents exclusively to achieve the physical form of the tablet than to enhance the drug efficacy or lowering dosage or frequency of administration. Direct compression is effected directly or after following the procedure of wet granulation. If we explore various digestible fibers from vegetable sources and extract the fibers using the same process as that of MCC, the drug delivery and additional effect of the base can be achieved simultaneously. The review article discusses various ingredients used in tablet formulation and their possible limitations and side effects. Further, the article also elaborates on various physiological, genetic, and tissue-related thrush-holds modifications in the human body viz., tachyphylaxis, tolerance, and other changes towards various drugs, and how such modifications pose an additional challenge in the treatment. Such challenges always compel us to look for newer drug molecules where a simple change in the delivery mechanism armamentarium of the tablet...
Read More
Posted by admin on Jan 31, 2022 in |
Blighia sapida a tropical evergreen plant with a dense crown, is commonly called ackee apple. Traditionally, the stem backs and leaves of the plant are used in the treatment of high fever, strokes, malaria, headache and some eye ailments. This study examined the antiplasmodial activity of Blighia sapida leaf extracts in comparison with the standard antimalarial drug Artemether-Lumefantrine combination, with a view to determining the changes in the parasitemia level in mice infected with Plasmodium berghei. The results showed a significant decrease in parasitemia level over six days period for mice treated with Artemether-Lumefantrine, ethanolic, and aqueous leaf extracts of B. sapida, whereas the controls showed a continuous increase. The parasitemia level was significantly reduced (P<0.05) in mice treated with 6.0mg/kg body weight of Artemether-Lumefantrine with 88% suppression; those treated with the ethanolic leaf extract at 50mg/kg and 30mg/kg body weight had parasitemia suppressed by 59% and 43.67% respectively. Parasitaemia count in mice treated with 50mg/kg and 30mg/kg body weight of aqueous leaf extract of B. sapida was suppressed...
Read More
Posted by admin on Jan 31, 2022 in |
Natural herb Ajwain, Trachyspermum ammi (L.) Sprague is an annual herbaceous plant belonging to the highly valued medicinally important family, Apiaceae; the essential oil from the fruits are the phenols, mainly thymol, and some carvacrol. The Indian Pharmacopoeia requires Ajowan oil to contain not less than 40 percent thymol. The remainder of the oil is called ‘thymene’. Thymene, which constitutes c. 45 percent of the oil, has the following composition: p-cymene, 50-55; gterpinene, 30-35; a- and ß-pinenes, 4-5; and dipentene, 4-6%. Presence of minute ‘amounts of camphene, myrcene, and D3-carene is also reported. Kapoor is a tree of many faces as it is a giant, stately forest tree native of the wet forests of tropical and subtropical regions of Asia. The species Camphora refer to camphor, an important chemical constituent present in the oil found in tree tissues. The botanical name is derived from the Greek language. It is derived from the word ‘kinnamomon’ which means spice. This herb is recorded in Sanskrit also. This is also used by...
Read More
