Posted by admin on Jun 30, 2020 in |
Bi-layer tablets are developed to get immediate and sustained delivery of various drugs that have pre-defined release. In the past few decades, development in a combination of active pharmaceutical ingredients (API) in a single fixed dosage form has increased in the pharmaceutical industry, also promotes patient convenience and compliance. Bi-layer tablet plays a crucial role in the development of controlled release in order to give a successful drug delivery. Bi-layer tablets can be said to be a better option to reduce chemical incompatibilities taking place between Active Pharmaceutical Ingredients and to enable the development of various drug release profiles. Bi-layer tablet suits for sequential release of two drugs in combination or to incorporate two incompatible substances in same tablet. The bi-layer tablets are preparing by using different techniques such as OROS® push-pulls Technology, L-OROSTM Technology, EN SO TROL Techno-logy. This review article explains various techniques of bi-layer tablets and why the development and production of quality bi-layer tablets need to be carried out and basic challenges faced during the...
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Posted by admin on Jun 30, 2020 in |
Medicinal plant is the basic and most significant part of the traditional medicinal system. The different plant contains medicinal properties, also known as an herbal plant. Bombax ceiba L plant of Bombacaceae family shows many Pharmacological activities. It is also called as Kate Savar and Semal. It is a native plant of western Africa. It is naturally obtained in Pakistan, India, and Myanmar. Bombax ceiba L. is a big and tall tree with a height of approximately 30m and having a diameter of 58 to78 cm. It grows in a straight direction with having a cylindrical stem and wide base. Bombax ceiba L contains principal constituents that are tannin and glycosides, which are present in part of leaf and stem. The part of the stem shows the presence of some lupeol and b-sitosterol, and the leaf shows the presence of alkaloid. The root bark contains the 3 naphthalene derivatives. Bombax ceiba L shows many pharmacological properties. The stem bark of plant used for the wound. Thorn of a plant...
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Posted by admin on May 31, 2020 in |
Treatment based on traditional medicine is very popular in the developing world due to inexpensive properties. There is a growing interest in herbal medicine. Curcumin a hydrophobic poly-phenol is derived from turmeric, the rhizome of the herb Curcuma longa L. Neurodegenerative diseases have become a major challenge for public health because of their incurable status. Curcumin has an outstanding safety profile and a number of pleiotropic actions with potential for neuroprotective efficacy, including anti-inflammatory, antioxidant, and anti-protein-aggregate activities. Because of its pleiotropic actions on the central nervous system, including preferential binding to amyloid proteins, Curcumin is being touted as a promising treatment for age-related brain diseases. This review article aims at gathering information predominantly on neurodegenerative...
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Posted by admin on Apr 30, 2020 in |
A novel coronavirus illness (COVID-19), activated by contamination with SARS-CoV-2, has frilled across 31 territories in China and more than 195 nations around the world. The change from the first side effects to intense respiratory trouble disorder (ARDS) is amazingly likely to be because of excessive cytokine discharge. There is a pivotal need to arrange sheltered and dynamic medications for activity. Chloroquine (CQ) presentations an inhibitory impact. In any case, the clinical utilization of CQ can cause serious reactions. Besides, hydroxyl chloroquine (HCQ) likewise shows an antiviral impact profoundly like that of CQ, restraining the cytokine storm by smothering T-cell enactment. Coronavirus immunization will be conveying after clinical preliminaries ahead in business...
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Posted by admin on Apr 30, 2020 in |
Oxalis corniculata Linn. is a medicinally important plant belonging to the family Oxalidaceae native to tropical and subtropical regions of the world. This paper briefly shows the botany, pharmacology, and therapeutic use of the herb. The review discloses that a varied array of phytochemical constituents have been extracted from the plant like glycosides, flavanoids, tannins, phytosterols, phenol, galactoglycero-lipid, volatile oil and fatty acids such as palmitic acid, oleic, linoleic, linolenic and stearic acids. The leaves contain flavonoids, isovitexine, and vitexine-2”- O- beta – D- glucopyrunoside. It holds essential activities like anti-inflammatory, anxiolytic, anti-epileptic, anti-fungal, anti-ulcer, anti-nociceptive, anti-cancer, anti-diabetic, hepatoprotective, anti-diarrhoeal, hypolipidemic, antioxidant, hypoli-pedemic, steroidogenic, cardioprotective, nephrotoxicity, diuretic, anti-microbial and wound healing has also been reported. These reports indicate that Oxalis corniculata has various therapeutic benefits and highlights the necessity for research and development on this...
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