Posted by admin on Jul 31, 2021 in |
The discovery of drugs for Alzheimer’s disease (AD) therapy that can also permeate the blood-brain barrier (BBB) is very difficult owing to its specificity and restrictive nature. The BBB disruption or drug administration directly into the brain is not an option due to toxic effects and low diffusion of the therapeutic molecule in the brain parenchyma. A promising approach for systemic drug delivery to the central nervous system is the use of nanosized carriers. The therapeutic potential of certain nanopharmaceuticals for AD has already been demonstrated in-vivo after systemic delivery. Herbosomes have an enhanced absorption rate, producing excellent bio-availability, good penetration power. Herbosome technology is one of such systems that incorporate phospholipids into standardized active ingredients of herbal extracts, thus effectively enhancing the bioavailability of water-soluble bioactive constituents of phytomedicines such as flavonoids, phenolics and hydrophilic compounds. These phytoconstituents have been established to exhibit a variety of biological activities that have pharmacological benefits. However, poor absorption of these phytoconstituents limits their bioavailability. The poor absorption is principally due to...
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Posted by admin on Jun 30, 2021 in |
Since the origin of life, plants have remained the primary source of food, shelter, and various remedial approaches. Plants are being in use for treating various kinds of diseases. Saraca asoca (Roxb.) de Wilde (Saraca indica L.) is a medicinal plant that belongs to the Caesalpiniaceae family (legume family). It is also called Ashoka. When Ashoka is split up into ‘a’ and ‘shoka’ represents a very deep meaning, i.e., freedom from the grief, which means happiness. It holds a very significant spot in Ayurveda and other traditional systems of medicine. It is the main ingredient in many Ayurvedic herbal formulations used in treating a variety of diseases. Ashoka is a very popular herbal plant for the treatment of female reproductive disorders. It maintains the reproductive health of females. It has many other useful biological properties like anti-microbial, anti-inflammatory, anti-ulcer, analgesic, haematoprotective, etc. The present review summarizes the phytomedicinal value of Saraca asoca in Ayurveda and the Folk system of...
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Posted by admin on Jun 30, 2021 in |
The wound healing method is thought of as mutually beneficial cellular and organic chemistry stages that classify measures to enhance the wound. Wound healing is outlined as stages that are finished by the body and delayed wound healing will increase the likelihood of microorganism infection. The improved wound healing method is performed by shortening the time required for healing or lowering the inappropriate happens. World Health Organization (WHO) and India have been promoting the use of traditional medicine because they are less expensive, easily available, strong belief among the community in developing countries, etc. Literature reveals that simple traditional plants are beneficial in treating several skin-related problems and for wound healing. Tridax procumbens Linn (Asteraceae) growing courtallam widely and surrounding regions peoples used who were suffered from minor cuts, scrapes. This plant easily available in any region of the world. Tridax daisy plant grows at all types of land escapes. In rainy seasons, it grows rapidly. This is an evergreen plant widely used for wound healing, which is helpful...
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Posted by admin on Jun 30, 2021 in |
It is a very old practice of using herbal plants for the maintenance of health. The demand for herbal remedies has been increased rapidly over the past few years. This is due to the beneficial health impacts of herbal products on the living systems. Cyperus rotundus, commonly called as nagarmotha, purple nutsedge or nutgrass, is a perennial grass that belongs to Cyperacea family. It is a cosmopolitan weed plant found in almost every corner of the tropical, subtropical, and temperate regions. It is a widely used plant in traditional systems of medicine, especially in Ayurveda and folk systems around the world, for its useful remedial properties in indigestion, constipation, dysentery, abdominal distention, cholera, skin diseases, diabetes, furuncle infections, sprains and bruises, fever and stomach ache, etc. It exhibits extraordinary therapeutic properties like antioxidant activity, antidiabetic activity, anti-inflammatory, antiplatelet, antimalarial, anti-diarrheal, anti-allergic, anti-tumor, analgesic activities, hepato-protective. The present review aims to provide information related to phytochemistry, traditional uses in Ayurveda and folk medicinal system, and therapeutic properties of Cyperus...
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Posted by admin on May 31, 2021 in |
Plants are naturally gifted for the synthesis of medicinal compounds & extraction is the first crucial step in the preparation of plant formulations. The extraction and characterization of active compounds from medicinal plants have resulted in the discovery of new drugs with high therapeutic value. The new recent extraction techniques with shortened extraction time, reduced solvent consumption, and increased pollution prevention concern and with special care for thermolabile constituents. In this article, the principle behind the operation of various extraction methods, factors influencing method performance, research progress, strength and weakness of different extraction approaches are discussed. The modern techniques for extraction of herbal plant secondary metabolites include Solid-phase micro-extraction, Supercritical-fluid extraction, Pressurized liquid extraction, Accelerated Solvent extraction, High-pressure solvent extraction, Membrane Extraction, The Cold finger method Stir-bar sportive extraction, Ultrasonic extraction, Acid-base extractions, Solid-phase extraction, Microwave-assisted extraction (MAE), Supercritical fluid extraction (SCFE), Pressurized solvent extraction...
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