THE PROMISING THERAPEUTIC EFFECTS OF RESVERATROL: A REVIEW OF HUMAN CLINICAL STUDIESAbstract
Resveratrol (3, 5, 4′-trihydroxy stilbene) is a type of natural phenol, produced by several plants in response to injury or under attack by pathogens. These phytoalexin compounds are thought to have antioxidant, anticancer, and anti-inflammatory properties. Although resveratrol is commonly used as a dietary supplement, there is no conclusive evidence of whether or not resveratrol could be a viable treatment in humans. Despite the richness of in-vitro and in-vivo research, which confirms its potential therapeutic effects, there is insufficient clinical evidence on its beneficial results in humans. In this review, we have focused on the mechanism of action of resveratrol and on clinical trials that have evaluated the efficacy of reseveratrol in cancer, cardiovascular diseases and neurodegenerative disorders.
D. Alkabbani * and E. Al-Khafaji
Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan Amman, Jordan.
05 May 2020
23 September 2020
29 September 2020
01 November 2020