ROLE OF TINOSPORA CORDIFOLIA AS IMMUNE BOOSTER CURRENT COVID -19 PANDEMICAbstract
Tinospora cordifolia (Gulvel) is traditionally used in ayurvedic medicine for apparently much varied conditions. It is commonly used in combination with other substances or sometimes alone. Supportive evidence from pharmacological studies suggests its prominent role in immune-modulation in conditions like diabetes mellitus, obstructive jaundice, and hepatic and splenic injury. Antioxidant, radioprotective, antihyperglycemic, anti-inflammatory, antiulcer and antispasmodic properties and capacity to dissolve urinary calculi also have supportive evidence. It is a potential antidepressant and enhances cognition and memory. Immune- modulation, preventing oxidative damage, and relieving inflammation are likely explanations for benefits in infections, joint inflammation, and allergies. The constellation of various activities plays a role in its protective effects against antitubercular and cytotoxic drugs, and toxins. It is helpful in potentiating other substances in the form of simple extraction. This review discusses its formulations, the relevance of supportive evidence and possible mechanisms of actions for its claimed benefits, and future prospects.
Vishal Thorat *, Firoj A. Tamboli, Asha Jadhav, Ravindra Gaikwad and Deepa Rangari
Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Shivaji University Kolhapur, Maharashtra, India.
17 June 2021
25 August 2021
28 August 2021
31 August 2021