PHYTOCHEMICAL SCREENING ASSESSMENT, ANTIOXIDANT CAPACITY AND ANTIMICROBIAL SUSCEPTIBILITY OF EXTRACTS FROM CECROPIA PACHYSTACHYA TRÉCUL. CECROPIACEAE (URTICACEAE) AS SOURCE FOR HERBAL MEDICINES DEVELOPMENTAbstract
Several plants used for medicinal purposes can be found in the Brazilian Cerrado, among which highlights the genus Cecropia used as a bronchodilator, antitussive, anti-diabetic, anti-diarrheal, anti-hypertensive, anti-inflammatory and vasorelaxant. Between species, there is Cecropia pachystachya belongs to the Urticaceae family. This study aims to evaluate the phytochemical screening, antioxidant capacity and antimicrobial susceptibility of ethanol, aqueous and hydroalcoholic extracts the leaves of C. pachystachya extracts. In analyzing, the phytochemical screening was used for prospecting technique chemical constituents of plant extracts to detect the presence of alkaloids, anthraquinones, steroids/triterpenoids, flavonoids, glycosides, tannins, and saponins. The method of inhibiting free radical 2, 2-diphenyl-1-picrylhydrazyl (DPPH•) was employed for the evaluation of the antioxidant capacity of the extracts and the antimicrobial susceptibility wells technique in Mueller-Hinton agar. The ethanol extract showed better antioxidant activity compared to the control with 0.56 µL/mL of IC50, but also in antimicrobial susceptibility with inhibitory effect in different concentrations. We can conclude that the extract which showed a high performance against the trials was the ethanol. However, C. pachystachya demonstrated to be a good candidate in the development of herbal medicines.
S. A. de Sousa, M. A. Alves, S. C. de Souza Silva, J. R. de Souza Nogueira, D. H. N. Martins, Y. M. Fonseca-Bazzo and A. C. Galdos-Riveros *
Faculty Anhanguera of Brasília, Distrito Federal, CEP 71950-550, Brazil
21 September 2015
26 November 2015
29 November 2015
30 December 2015