PHYTOCHEMICAL INVESTIGATION AND IN-VITRO ANTI-ARTHRITIC EVALUATION OF VARIOUS EXTRACTS OF FICUS AURICULATA LOUR. LEAVES

Plants have been used for medical purposes since prehistoric periods. Approximately 60% of the world population and 80% of the population of developing countries depend on traditional medicinal plants due to their safety, accessibility, affordability and they are more economic. Inflammation of the joints is known as arthritis. More than 100 distinct forms of arthritis and associated disorders that affect the joints are referred to as arthritis, which is not a single illness. The connective tissue that envelops joints and other tissues. Anti- arthritic activity was mainly reducing the total leukocyte migration as well as lymphocyte and the monocytes / macrophage migration. The current study was designed to evaluate the in-vitro anti- arthritic activity of various extracts like Pet ether, Chloroform, Ethanol, Aqueous of Ficus auriculata Lour leaves. The extraction was done by using Soxhlet apparatus method (Pet ether, Chloroform, Ethanol) and maceration method was done for aqueous extract and the extract was subjected to phytochemical screening. The in vitro anti arthritic activity of various extracts was performed by using the bovine serum protein denaturation method. The result revealed that various extracts contain phytochemical constituents like alkaloids, flavonoids, glycosides, phenols and tannins and carbohydrates. The various extracts exhibited significant in-vitro anti arthritic activity when compared to the standard drug (Diclofenac) respectively.