PHYTO CHEMICAL INVESTIGATION AND WOUND HEALING ACTIVITY OF JASMINUM GRANDIFLORUMAbstract
The influence of roots and leaf extracts of Jasminum grandiflorum was studied for its wound healing activity using the excision wound model. The roots and leaves of Jasminum grandiflorum were extracted with alcohol 90%, were subjected to phytochemical investigation. The root and leaf extracts were screened for wound healing activity. The animals were divided into four groups in excision wound model; controls were treated with normal saline, standard were treated with betadine and the experimental groups were treated with root and leaf extracts of Jasminum grandiflorum till complete epithelisation. The leaf extract treated wounds were found to epithelise faster as compared to the control group. Leaf extract treated rats exhibited 61.346% reduction in the wound area when compared to the control of 55.72%. The demonstration of an increased rate of wound contraction findings suggests the use of Jasminum grandiflorum leaf extract in the management of wound healing.
B. S. Hunasagi *, M. Somashekhar, N. V. Kalyane and E. N Gaviraj
Department of Phytochemistry, BLDEA’S SSM College of Pharmacy and Research Centre, Vijaypur, Karnataka, India.
09 February 2018
25 March 2018
30 March 2018
01 June 2018