IN-VITRO ANTIUROLITHIATIC ACTIVITY OF MACERATED AQUEOUS EXTRACT OF TERMINALIA CHEBULA BY USING TITRIMETRY METHODAbstract
Urolithiasis is a complex process that occurs from the various physiochemical event, including super-saturation aggregation, nucleation, growth, nucleation within the kidney. Data from different types of studies revealed that phytomedicines useful as an alternative remedy for the management of Urolithiasis. Terminalia chebula has been reported to possess antiurolithiatic property. The fruits were extracted in aqueous by maceration. In-vitro study was conducted to study the anti-urolithiatic effect of fruits of a macerated aqueous extract with standard drug Cystone. The titrimetric method was performed to evaluate the dissolution of stone crystal. Aqueous extract of fruits of Terminalia chebula proved a significant effect compared with standard drug Cystone. Aqueous extract of fruits of Terminalia chebula dissolves 48% crystal while Cystone dissolved 62% calcium oxalate crystal in an in-vitro study.
V. Anu *, S. Akhila, I. A. Kumar and S. Antony
Department of Pharmacognosy, KVM College of Pharmacy, Kokkothamangalam, Cherthala, Alappuzha, Kerala, India.
03 April 2020
23 June 2020
28 June 2020
30 June 2020