IN-VITRO ANTIOXIDANT AND ANTIBACTERIAL STUDY OF BACCAUREA RAMIFLORA SEEDSAbstract
Baccaurea ramiflora, which is commonly known as Burmese grape, is a commonly used medicinal plant in South Asian folk medicine. They are potent in treating dermatological disorders and constipation. The study aims to investigate the possible biological activities of B. ramiflora by determination of antioxidant activities of total ethanolic extracts through the free radical scavenging activity over vitamin C and the antibacterial activity using the disk diffusion method. In-vitro antibacterial activity was evaluated against E. coli, P. aeruginosa, and S. aureus and Azithromycin was used as the reference compound. IC50 was found to be 27.57 and 13.66 µg/ml for B. ramiflora and vitamin C respectively, and the ethanolic plant seed extract exerted significant antibacterial activity at 500 µg, 1000 µg/disc concentration over the standard antibiotic drug which demonstrates the efficacy of B. ramiflora plant seeds extract.
P. S. Podder *, R. Das and S. K. Kundu
Department of Pharmacy, Faculty of Biological Science, Jahangirnagar University, Savar, Dhaka, Bangladesh.
09 June 2018
04 July 2018
09 July 2018
01 September 2018