EVALUATION OF THE AQUEOUS EXTRACT OF THE TRUNK SCRAPS OF TERMINALIA IVORENSIS (COMBRETACEAE) ON THE CICATRISATION OF SKIN LEASES IN DIABETIC RATS (RATTUS NORVENGICUS)
AbstractThe complication most feared by diabetics remains the diabetic foot, due to the risk of amputation. Terminalia ivorensis belongs to the Combrétacée family and is rich in secondary metabolite products. Studies have shown that Terminalia ivorensis has antifungal potentiaĺ and is traditionally used to treat wounds. Topical application based on Terminalia ivorensis on wounds of rats rendered diabetic showed a rapprochement between the results given by this application and L-mesitran® used as a reference molecule. The aqueous extract at different concentrations (500, 1000 mg/ml) showed significant healing activitý after topical administration in rats.
Article Information
8
393-401
1094 KB
88
English
IJP
Koffi Severin *, Yao Konan Bertin, Abizi Georges, Dongo Kobenan Firmin and Ouattara Fatou Shcherazadeepouse Soro
Laboratory of Animal Biological Sciences, UFR of Sciences and Technology, Alassane Ouattara University, BPV 18 Bouake 01, Ivory Coast.
severinokoffl@gmail.com
17 April 2025
08 May 2025
23 May 2025
10.13040/IJPSR.0975-8232.IJP.12(5).393-01
31 May 2025
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