COMPARATIVE STUDY OF IN VITRO ANTHELMINTIC ACTIVITY OF SAP OF AZADIRACHTA INDICA (NEEM)Abstract
The present study was designed to judge the in vitro anthelmintic activity of sap of Azadirachta indica. The duct roundworm, Pheretima posthuma, has been reported to cause severe health issues in immeasurable folks round the world. Records prove that a lot of the liquid extracts obtained from varied elements of various seasonal plants exhibited significant anthelmintic activity against Pheretima posthuma. This gave us a lead to a found new compound resulting in the anthelmintic activity on sap of Azadirachta indica. The vermicidal activity was studied in four completely different volumes (5, 10, 20, 40 ml) and dilutions (5/10, 10/10, 15/10, 20/0) milliliter was prepared. The dilutions were evaluated for the time of palsy and time of the death of the worm. The sap of Azadirachta indica exhibited important anthelmintic activity. At the highest concentration of 40 milliliters and dilution’s 20/0 milliliter exhibits wonderful anthelmintic activity was reported as compared to the standard drug, Albendazole. The sap of Azadirachta indica in vitro studies indicated that sap of Azadirachta indica possesses significant anthelmintic activity.
T. Singh *, A. Mishra, S. I. Ul haq and A. Lavanya
Guru Nanak Institutions Technical Campus, School of Pharmacy, Ibrahimpattnam, Hyderabad, India
31 October 2016
23 November 2016
26 December 2016
31 December 2016