BENEFICIAL ROLE OF CURCUMIN IN DISEASES TREATMENTAbstract
Curcumin regulates cellular signaling pathway related to cancer growth, inflammation and apoptosis and due to biological activities can be target DNA, RNA, and enzymes. Also, curcumin has an inhibitory effect against MARK, P53, β-catenin, and AKT. It can be considered as a promising agent to treat many diseases, but it is important that should be acceptably carried out cellular targeting with curcumin. Here, we reviewed the beneficial effects of curcumin in the treatment of diseases. Our review study was confirmed that curcumin has a potential effect in diseases treatment, but there is a dire need for an increase of its bioavailability to the promotion of its efficacy. We suggest that should be design the methods for increase of cellular targeting by curcumin in further studies.
S. H. Hassanpour *, M. A. Dehghani, S. M. Alipour, S. Z. Karami and F. Dehghani
Young Researchers and Elite Club, Yasooj Branch, Islamic Azad University, Yasooj, Iran.
11 January 2018
05 February 2018
13 February 2018
01 June 2018