ANTIBACTERIAL ACTIVITY OF ETHANOL EXTRACT OF LEAVES OF HUGONIA MYSTAXAbstract
The objective of this research is to evaluate the preliminary phytochemical analysis and antibacterial activity from the medicinal plant of Hugonia mystax of Dindigul district, Tamil Nadu. The leaves of plant Hugonia mystax was subjected to Soxhlet extraction process by using solvent ethanol. Preliminary phytochemical analysis of ethanol extract of Hugonia mystax leaves showed the presence of carbohydrate, flavonoids, phenolic groups, saponins, steroids, tannins, and terpenoids. In-vitro antibacterial activity was performed by the plate hole diffusion method in MH agar medium. The bacteria used for the antibacterial study were Bacillus lichenformis (NCIM 2468), Brevibacterium luteum (ATCC 15830), Escherichia coli (ATCC 11775), Flavobacterium devorans (NCIM 2581), Klebsiella pneumonia (ATCC 11229), Micrococcus flavus (NCIM 2984), Micrococcus luteus (NCIM 1207). Ethanol extract of Hugonia mystax exhibited the best result of the maximum zone of inhibition observed against gram-positive as well as gram-negative bacteria. The anti-bacterial activity revealed the medicinal potential of Hugonia mystax to develop a drug against human ailments.
B. Vasuki* and R. Sambathkumar
Department of Pharmaceutical Chemistry, J. K. K. Nattraja College of Pharmacy, Komarapalayam, Namakkal, Tamil Nadu, India.
06 October 2017
14 November 2017
18 November 2017
01 February 2018