AN EVALUATION OF ANTI-DIABETIC ACTIVITY OF CALOTROPIS PROCERA LEAF EXTRACTION (AAK PALNT)
AbstractAim: This study reviews the anti-diabetic property of Calotropis procera leaf extract. Calotropis procera used for different pharmacological activities. Calotropis procera has a number of phytoconstituents which are: Cardenolides, Terpenes, Flavonoids, Enzyme and other more components which are used to treat a number of diseases. They have some pharmacological activities like: cytotoxic activity, anti-diabetic, antioxidant, analgesics, anti-inflammatory, anti-arthritic, anthelmintic, antimicrobial, wound healing, hepato-protective, immune response, myocardial infarction and so on. Calotropis procera plant which is used to treat diabetes, it inhibit the α-amylase and α- glycosidase enzyme that are responsible for increasing the blood glucose level. Methanolic Extraction and Aqueous extraction of the Calotropis procera leaf is used as a drug. We also can use these extractions in novel technologies to treat the disease. It was studied by in-vitro testing of the extraction, which inhibits the particular enzyme by the non-competitive enzyme inhibition mechanism. Calotropis procera having a major effect of anti-diabetic inhibits these enzymes. Calotropis procera is the major source of anti-diabetic agents acting on the carbohydrate enzymes that are α- amylase and α- glycosidase. This study is revealed the anti-diabetic effect of Calotropis procera.
Article Information
5
330-336
806 KB
297
English
IJP
Mohd Aalam *, Gulafshan Parveen and Chavi Mittal
Guru Nanak College of Pharmaceutical Sciences, Jhajra, Dehradun, Uttarakhand, India.
gulafshanmirza12345@gmail.com
05 June 2023
27 June 2023
29 June 2023
10.13040/IJPSR.0975-8232.IJP.10(6).330-35
30 June 2023