A PROMISING BIOACTIVE COMPONENT TERPINEN-4-OL: A REVIEWAbstract
Since, the middle ages, essential oils have been widely used for bactericidal, fungicidal, insecticidal, virucidal, cosmetic and medicinal applications, especially nowadays in agriculture, food, sanitary and pharmaceutical industries. Distillation is the common mode of extraction used for aromatic plants, which results in a variety of volatile molecules such as terpenes, terpenoids, aliphatic components, and phenol derived aromatic components. Extensive research has been done in the last decade to screen and evaluate the pharmaceutical potential of the phytochemical constituent, terpinen-4-ol. It is found in various plants species and has gained attention because of its antiviral, antibacterial, anti-inﬂammatory and antifungal properties. This monoterpene is a bioactive component of tea tree oil (TTO) present in a plant belonging to the genus Melaleuca. In the present review, an overview of the current status and knowledge on the physicochemical properties, analytical techniques, formulations, pharmacological applications, irritation and toxicity potential of terpinen-4-ol have been discussed.
E. Yadav and R. Rao *
Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, Haryana, India.
22 July 2016
19 August 2016
27 August 2016
31 August 2016