A BRIEF REVIEW ON SOLANUM XANTHOCARPUM ALONG WITH THE EVALUATION OF ANTICANCER POTENTIAL IN CARPESTEROLAbstract
The “deadly nightshade” family, commonly known as “black nightshades,” it’s also used as a traditional medicine system in a country like India and China. Solanum xanthocarpum is known to contain alkaloids, steroids, glycol-alkaloids, steroid saponins, glycoproteins, that exhibit antitumor activity. This review explores the phytopharma-cological properties of Solanum xanthocarpum and summarizes its wide range of pharmacological applications to understand and integrate potential image issues as multipurpose medicines. Solanocarpidine and a phytosterol known as Carpesterol are also present. The seed oil contains Carpesterol. Diosgenin, lanosterol, sitosterol. Solasonnine, solamargine, and solasodine have been isolated from the plant. The roots and fruits are used for medicinal purposes. The herb is useful both internally as well as externally. The apoptotic effects and the amount of DNA fragmentation increased in a dose-dependent manner after the treatment with the protein. Authors believe this glycoprotein is a natural anticancer agent due to its potential to induce apoptosis in the HTC29 cell.
Ranjan Kumar Singh *, Ajay Garg and Khushboo Shrimali
Department of Pharmacology, Shekhawati Institute of Pharmacy, Sikar, Rajasthan, India.
26 February 2022
26 April 2022
28 April 2022
30 April 2022