“A BRIEF REVIEW ON PHYTOCHEMICALS REPORTED TO PREVENT ALZHEIMER’S DISEASE”
AbstractAlzheimer’s disease (AD) is a multifaceted, progressive neurodegenerative illness marked by memory loss, personality changes, and cognitive impairment. While the actual origin of AD is unknown, recent research points to lifestyle, nutrition, environmental, and genetic factors. Genetic factors play a role in illness progression. To present, pharmaceutical therapies have not affected disease progression. Over the last decade, more than 200 potential therapeutic candidates have failed clinical trials, indicating that the disease and its causes are likely to be complicated. Since, a long time ago, products made from natural resources, such as medicinal plants, have been used to treat various memory diseases, including amnesia, dementia, Alzheimer’s, and Parkinson’s. Various studies have shown the use of medicinal herbs in treating Alzheimer’s. Despite this, it is still unclear exactly how they act. Numerous bioactive chemicals, including polyphenols, tannins, flavonoids, triterpenes, alkaloids, and sterols, have been found in diverse plant components after phytochemical examinations. These substances have various pharmacological properties, including antioxidant, anticholinesterase, anti-inflammatory, anti-amyloidogenic, and anti-inflammatory effects. Several medicinal plants against AD are described in this review.
Article Information
1
337-352
1217 KB
480
English
IJP
Shraddha P. Gaikwad *, Vaishnavi S. Magar and Shailaja B. Jadhav
Department of Pharmaceutical Chemistry, P. E. S Modern College of Pharmacy, Nigdi, Pune, Maharashtra, India.
gaikwadshraddha1999@gmail.com
18 July 2023
26 July 2023
28 July 2023
10.13040/IJPSR.0975-8232.IJP.10(7).337-52
31 July 2023