Posted by admin on Jan 31, 2020 in |
The objective of the present study is to develop the pharmacognostic and phytochemical profiles of Ruellia tuberosa L. leaf and root. The present study considers the detail investigation of macroscopy, microscopy, preliminary qualitative phytochemical analysis, physicochemical evaluations, and chromatography profiling. The microscopical investigation was adopted to identify the cellular powder characters of leaves and roots, including diacytic stomata, few sessile glandular trichomes, profuse oil globules, exfoliating cork, few small schizogenous oil cavities, cystolith, etc. Physicochemical parameters reveal the data of quality, purity while phytochemical screening reflects the presence of various secondary metabolites. The chromatographic fingerprint data represent the authenticity of plant sample. Data obtained from botanical and chemical screening in combination may be considered as standard for identification and authentication of leaves and roots and may be helpful in developing pharmacopoeial...
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Posted by admin on Jan 31, 2020 in |
The objective of the study was to formulate and evaluate the antioxidant activity and the wound healing effect of the Punica granatum peel extracts formulation. Tannins, alkaloids, flavonoids, proteins, and phenols were present in the ethanolic extract, which is further formulated in a gel formulation. Seven herbal gel formulations were prepared using 1.5% of the gelling agent’s carbopol 940 (F1-F7). Formulations were evaluated for physical appearance, viscosity, extrudability, pH, and spreadability. The antioxidant study was evaluated in-vitro, using 2, 2-diphenylpicrylhydrazyl (DPPH), and reducing power assays. It was found that all the gel formulation has good power to inhibit DPPH and good reducing power. The antimicrobial properties were evaluated by agar well diffusion method. The result indicated that F5 and F7 exhibited good antimicrobial properties. The highest potential was observed in the F7 against E. coli and B. subtilis. Wound healing was studied using excision wounds on rat models. Treatment of wound with a gel containing 2% and 10% (w/w) ethanolic extract exhibited better-wound healing activity than the positive control....
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Posted by admin on Jan 31, 2020 in |
From ancient times, various natural products are used as food and as medicine for the treatment of diseases. In the last few decades, herbal medicine has been used in the field of medicine because of its natural origin and lesser side effects. One such medicinal plant is Juglans regia (Family: Juglandaceae). The plant is also known as Persian walnut, English walnut, white walnut, or in common known as walnut. All parts of this plant viz. bark, kernel, leaves, etc. are extensively useful. Traditionally the kernels of walnut are used for the treatment of diabetes, asthma, gastric cancer, prostate cancer, liver damage, malaria, arthritis, toothache, dermal inflammation, etc. by the folk of different countries. Whereas researchers worldwide also proved that different parts of Juglans regia (JR) also possess beneficial effects such as anti-oxidant, anthelmintic, insecticidal, hepatoprotective, anti-inflammatory, anti-diabetic, wound healing, anti-depressant, fungicidal, anti-microbial, anti-nociceptive, anti-cancer, analgesic, immunomodulatory, lipolytic, neuroprotective and many other medicinal properties. Chemical analysis indicates that presence of various phytochemicals like alkaloids, flavonoids, carotenoids, glycosides, saponins, polyphenols, omega...
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Posted by admin on Jan 31, 2020 in |
Realising the immense medicinal values of secondary metabolites in drug formulations, the present study was conducted on an important sec metabolite i.e., ellagic acid (tannin) in in-vivo (leaf) and in-vitro callus tissues of Woodfordia fruticosa a much used medicinally important plant. The present method provided a quick and easy approach for the detection and quantitation of biomarker ellagic acid. Qualitative analysis showed the presence of ellagic acid in both in-vivo and in-vitro (callus) samples of Woodfordia fruticosa. Analytical method high-performance thin-layer chromatography (HPTLC) was developed for the quantification of ellagic acid in in-vivo and in-vitro samples of the various solvent systems tried, the system containing toluene-ethyl acetate-formic acid-methanol (3:3:0.8:0.2 v/v) gave the best resolution of ellagic acid (Rf 0.65) from the other components of the sample extracts, and enabled their simultaneous quantification. Quantitative evaluation of the plate was performed in the remission/absorption mode at 280 nm by the use of a TLC Scanner III CAMAG. The amount of ellagic acid was estimated to be about 0.21% w/w for leaf...
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