Posted by admin on Jun 30, 2018 in |
Trichosanthes cucumerina var. cucumerina Linn. is an annual monoecious climber. Trichosanthes cucumerina var. cucumerina Linn. mainly distributed in Asian countries like India, Sri Lanka, Bangladesh, Burma, Malaysia, and Australia. Trichosanthes cucumerina var. cucumerina is a wild variant (Cucurbitaceae) the major active components are triterpenoids, saponins, and cucurbitacins; chemical constituents like flavonoids, carotenoids and phenolic acids are also present. Trichosanthes cucumerina var. cucumerina is used in the treatment of headache, alopecia, fever, abdominal tumors, bilious, boils, acute colic, diarrhea, haematuria, and skin allergy, etc. Trichosanthes cucumerina is used as an abortifacient, vermifuge, refrigerant, purgative, malaria, laxative, hem agglutinant, emetic, cathartic, bronchitis and anthelmintic. The present study involves the pharmacognostical and phytochemical studies of the plant. The transverse section was taken for the microscopical studies. Powder microscopy shows the presence of annular, spiral, cylindrical, tubular and thick-walled xylem vessels. Different physicochemical evaluation ash value, extractive value, fluorescence analysis, etc, were performed. Phytochemical evaluation is performed for the ethanolic extract of leaves presence of alkaloids; flavanoids, glycosides, phenols, etc. are...
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Posted by admin on Jun 30, 2018 in |
The mulberry has been widely cultivated to feed silkworms. The leaves of mulberry have been used in traditional medicine as an analgesic, antitussive, cathartic, diuretic. In this study, we have isolated three compounds (LC1-3) by chromatographic methods from the mulberry leaves (Morus alba L.) collected in Thai Nguyen province, Vietnam. These compounds were identified as Kaempferol-3, 7-di-O-α-L-rhamnopyranoside (LC1), 7, 4’- dihydroxy-5, 3’- dimethoxyflavone (LC2), (S)-5, 5’, 7-trihydroxy-2’, 4’-dimethoxy-6-methylflavanone (LC3). Their structures were elucidated by spectroscopic methods, including MS and NMR. Compound LC3 was isolated from mulberry leaves for the first time. These compounds were evaluated the tyrosinase inhibitory activity in-vitro. Our data showed that compound LC3 has potential tyrosinase inhibitory effects with IC50 values of 15.48 ± 2.96...
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Posted by admin on Jun 30, 2018 in |
Helminthiasis is prevalent globally, but is more common in developing countries with poorer personal and environmental hygiene. In the human body gastrointestinal tract is the abode of many helminths, but some also live in tissue. They harm the host by depriving him of food, causing blood loss, injury to organs, intestinal or lymphatic obstruction. It is estimated that hundreds of millions of people harbor parasitic worms and one-third of the almost three billion people that live below the poverty line in developing regions of Sub-Saharan Africa, Asia, and the Americas are infected with one or more helminth. This review gives an overview of symptoms, diagnosis, treatment, prevalence, and herbs used in...
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Posted by admin on Jun 30, 2018 in |
Present communication deals with the pharma-cognostical standardization on the roots of Agnimantha (Premna serratifolia L. (syn. P. integrifolia L.) belong to the family Verbenaceae. It is an important medicinal plant used in many Ayurvedic formulations. According to Ayurveda the roots and leaves are the most useful parts of the plant. It is one among the Dashamula. Macro, microscopical and physicochemical studies were carried out as per the latest Ayurvedic Pharmacopoeia of India, part-1, volume-8 protocols to establish its Pharmacognostical standards. Studies revealed the presence of abundant, simple to compound starch grains with prominent hilum in the center, cork cells filled with yellowish brown pigmented cells, starch grains in the medullary rays, abundant xylem vessels with bordered pits and tracheids with pits, prism-shaped crystals in the cortex region. Phytochemical studies showed the presence of carbohydrates, alkaloids, phenols, tannins,...
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Posted by admin on Jun 30, 2018 in |
Before the advances in synthetic chemistry and discovery of antimicrobials in the 19th early to 21st centuries, plants provided the major source of medicines. Traditional knowledge is more and more an established resource for modern medical science. Ayurveda is the most ancient health care system and is practiced widely in India, Sri Lanka and other countries. This article reviews some of the past success of the natural products approach and also explores some of the reasons why it has fallen out of favour among major pharmaceutical companies and challenge in drug discovery from natural products especially higher plants. In this review we consider the past, present and future value of employing information from plants used in traditional medical practice for the discovery of new bioactive...
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