Posted by admin on May 17, 2016 in |
Gynura procumbens (GP) commonly known as longevity spinach is one of those precious medicinal herbs of Asteraceae that are still included in a un-utilized herb in spite of the variety of useful pharmacological properties it possesses. It is mainly popular in South-East Asian countries for its traditional medicinal properties. It is usually used as a traditional medicine for the treatment of inflammation, herpes simplex virus, rashes, fever, rheumatism, kidney diseases, migraines, diabetes mellitus, cancer, and hypertension. This article provides the collective information about the phytochemical constituents isolated from leaves of this plant used in a modern scenario for the treatment of various ailments like kaempferol-3-O-rutinoside, astragalin, rutin, kaempferol, sterol glycosides, flavonoids, saponins, tannins, and terpenoids, etc. Here, we have reviewed all the reported pharmacological properties such as anti-inflammatory, anticancer, anti-diabetic, anti-herpes simplex virus, anti-ulcerogenic, vasorelaxant, toxicity, and some other...
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Posted by admin on Apr 23, 2016 in |
The present study was aimed to find out the antimicrobial potential of acetone extract of Acacia concinna leaf against five different bacterial strains at 100 and 200mg/ml concentrations. The disc diffusion assay was performed to access the antimicrobial potential of the extract. The agar plate containing a bacterial culture was divided into 4 zones, and each zone was independently impregnated with four sterile filter paper discs (6 mm in diameter) containing (10 µl of each concentration) distill water (Negative control), ampicillin (Positive control); Acacia concinna leaf extract (100 mg/ml and 200 mg/ml as test). Zone of inhibition and MIC (minimum inhibitory concentration) for test drug was evaluated to access the antimicrobial potency. The phytochemical analysis shows the presence of alkaloids, tannins, and glycosides that might be responsible for the aimed biological activities. Out of five bacterial strains, the test drug exhibit zone of inhibition against Mycobacterium smegmatis and Bacillus subtilis in a concentration-dependent manner. Minimum inhibitory concentration (MIC) of test drug against Mycobacterium smegmatis and Bacillus subtilis, was found...
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Posted by admin on Apr 23, 2016 in |
To access the quality of drug the standardization is very critical. As per WHO guidelines, 80% of the peoples have relied on traditional medicine in a rising nation. Most of the conventional system is valuable but a lack of standardization. The parameters studied are physicochemical parameters, phytochemical parameters & qualitative chemical tests. These values will help to obtain the batch to batch variation in traditional preparation of Mehari Choorna which is used to treat diabetes mellitus. We calculated and discussed extractive values, moisture content and ash value. The scientific method for its quality and safety evaluation is not yet to be documented. Hence in the current work, an attempt has been made to evaluate the quality parameters to be used for its preparation and...
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Posted by admin on Apr 23, 2016 in |
Over-harvesting of many traditional medicinal plants has become a threat to the country’s species diversity and has resulted in the endangerment of certain medicinal plant species. Shortly, many plant species may be unavailable for the use of industry due to over-exploitation. The present study outlines the concept of plant part substitution. The studies were carried out in Ailanthus excelsa to evaluate the possibilities of using small branches in place of stem bark which will help sustainable utilization. Stem bark and small branches of Ailanthus excelsa are compared by the physicochemical analysis, phytochemical analysis, total phenolic contents, total flavonoid contents and High-Performance Thin Layer Chromatography (HPTLC). Phytochemical analysis and HPTLC of n-hexane, ethyl acetate, and ethanol extracts showed many similarities which suggest that small branches may have nearly similar active potency like stem bark and may provide the base for further study to use small branches as a substitute of stem bark of Ailanthus excelsa. The study will be helpful in identification and quality control of Ailanthus excelsa and can...
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Posted by admin on Apr 23, 2016 in |
Protective effect of the probiotic combination of usnic acid and Lactobacillus casei in experimentally induced ulcer in rats was investigated. Rats inward usnic acid (100 mg/kg), L. casei (10-8 con.), usnic acid (100 mg/kg) + L. casei (10-8 con.), and omeprazole (30 mg/kg) twice daily for 5 days for prevention against aspirin (ASP), ethanol (EtOH), cold restraint stress (CRS) and pylorus ligation-induced ulcer (PL). The results of the present study showed the first time that the usnic acid (100 mg/kg) + L. casei (10-8 con.) as probiotic combination significantly inhibited the ulcer index in ASP, EtOH, CRS and PL to 3.4 ± 0.12, 6.3 ± 1.8, 3.4 ± 0.8 and 4.3 ± 0.9 (p<0.001) respectively, as compared to control group (19.2 ± 1.6, 22.5 ± 6.3, 24.2 ± 3.2, 14.2 ± 2.7). Besides usnic acid (100 mg/kg) + L. casei (10-8 con.) offered protection (72%, p<0.001) against ethanol-induced depletion of gastric wall mucus. The usnic acid (100 mg/kg) + L. casei (10-8 con.) showed significant inhibition of lipid peroxidation...
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