Posted by admin on Feb 28, 2025 in |
Acalypha indica, an herbaceous plant indigenous to tropical areas, has been extensively utilized in traditional medicine for the treatment of various health issues. This review presents a thorough overview of its medicinal attributes, phytochemical composition, and pharmacological effects, emphasizing its promise in drug development. Extracts from this plant have shown notable anti-inflammatory, antimicrobial, antioxidant, and anticancer activities, positioning it as a viable candidate for innovative therapeutic solutions. Historically, Acalypha indica has been employed in traditional practices for healing wounds, addressing respiratory ailments, and managing gastrointestinal disorders. Phytochemical investigations have revealed significant bioactive compounds, such as flavonoids, alkaloids, tannins, and anthraquinones, which play a role in its pharmacological properties. Preclinical research has assessed its effectiveness against bacterial and fungal infections, diseases related to oxidative stress, and cancer, yielding promising outcomes. However, obstacles such as the need for extract standardization, concerns regarding toxicity, and a scarcity of clinical studies impede its advancement. Future investigations should aim to clarify its mechanisms of action, refine dosage formulations, and conduct clinical trials to confirm...
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Posted by admin on Jan 31, 2025 in |
The review delves into the latest developments in dengue fever treatment, particularly focusing on emerging therapies such as vaccines and host-directed therapies (HDTs) designed to bolster the immune response to the virus. It outlines the progress in vaccine research, with a particular emphasis on the introduction of Dengvaxia, the first licensed dengue vaccine, and highlights ongoing efforts to develop more effective vaccines that offer broader protection across different serotypes of the virus. The review also underscores the importance of a holistic approach to managing dengue fever. It argues that alongside medical interventions, factors such as dietary considerations and community engagement are crucial in prevention strategies. It stresses the need for integrated public health initiatives that empower local communities to take proactive measures in controlling mosquito populations and reducing the risk of transmission. Furthermore, the review calls for sustained research efforts and collaboration across multiple sectors, including healthcare professionals, scientists, and policymakers. By fostering international cooperation, the hope is to develop innovative solutions that can effectively reduce the global burden...
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Posted by admin on Jan 31, 2025 in |
Beta vulgaris is commonly called beetroot. This is the taproot portion of the beet plant. There are types of beets grown in Egypt, India, Europe and Ukraine. It is used in the traditional Indian system of medicines. Beta vulgaris Linnaeus is among the top ten most powerful vegetables as an excellent source of phytochemicals. It is also known for its high content of biologically active substance such as betalains, polyphenolic compounds, vitamin, carotenoids and other nutrients including sodium, potassium, and magnesium. Some parts of this plant are used in the medicinal system as antioxidant, antidepressant, antimicrobial, antifungal and anti-inflammatory, diuretic, expectorant and carminative. Beet (Beta vulgaris L.) as a health-promoting functional food may be potentially beneficial in cancer. As a source of polyphenol, flavonoids, dietary nitrates and other beneficial nutrients, beetroot supplementation may provide a holistic way to prevent cancer and manage the side effects of...
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Posted by admin on Jan 31, 2025 in |
Morinda citrifolia, known as Indian mulberry, Nuna, or ach in India and “Morinda citrifolia (Noni)” in Hawaii and Polynesia, a medicinal plant with a long story of traditional use. It possesses numerous biological activities, including antibacterial, antiviral, antifungal, anticancer, anthelminthic, analgesic, hypotensive, anti-inflammatory, and immune-boosting effects due to its diverse phytochemicals. Its increasing popularity has led to its incorporation into various products across industries, serving as a natural source for chemical reagents, eco-friendly pesticides, and medications. Different parts of Morinda citrifolia, such as the fruit, seeds, bark, leaves, and flowers, are utilized for their unique nutritional and therapeutic benefits, particularly the fruit, valued for its rich chemical composition. This review explores the botany, ethno-pharmacological applications, phytochemistry, pharmacological activities, safety and quality, economic potential, and marketed products of Morinda citrifolia’s fruit, seeds, leaves, and roots. Additionally, it examines the phytochemical compounds identified through in-vitro and in-vivo...
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Posted by admin on Jan 31, 2025 in |
Context: Epilepsy is a neurological disorder of brain in which the clusters of neurons, occasionally signal abnormally and cause strange emotions, sensations, and behavior, or sometimes muscle spasms, convulsions, and loss of consciousness. Lagenaria siceraria (Molina) Standley (LS), commonly known as “bottle gourd” (English), possesses several medicinal properties; little is known about its action as a nerve tonic. Objective: The purpose of this study was to characterize (or to study) the anti-epileptic potential of the bioactive fractions of methanolic extract of LS fruits through pharmacological screening. Materials and Methods: The experiment was conducted in specific animal models i.e., Pentylenetetrazole (PTZ)-induced convulsions and Maximal electroshock-induced seizures (MES) in Swiss albino mice to evaluate anti-epileptic effects. The effect of the fractions was also tested on motor coordination using the rota-rod apparatus. Results and Conclusions: Preliminary phytochemical screening of the methanolic extract of LS and its fractions showed a huge range of phytoactive compounds. Among all the fractions, chloroform and acetone fractions were found to have more number of such phytoactive compounds....
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